In this study ultrasound has been utilised for the Fischer glycosylation using free sugars and sulphuric acid immobilized on silica as catalyst. N-acetyl-d-glucosamine, N-acetyl-d-galactosamine, d-glucose, d-galactose, d-mannose, l-fucose, and lactose were glycosylated with propargyl alcohol or 2-azidoethanol affording the corresponding glycosides, with the production of the $\alpha$-glycopyranoside as the dominant product. Remarkable acceleration of the glycosylation reactions (15 min–2 h compared to several hours) over reported procedures together with good yields were always observed
Dr. Nasrin Shaikh, Russo, L., Cipolla, L., and Nicotra, F., “Ultrasonic assisted Fischer Glycosylation: Generating Diversity for Glycochemistry”, Molecular Diversity, vol. 15, pp. 341–345, 2011.