Publication Type:

Journal Article

Source:

Molecular Diversity, Volume 15, Number 2, p.341–345 (2011)

URL:

https://doi.org/10.1007/s11030-010-9281-2

Abstract:

In this study ultrasound has been utilised for the Fischer glycosylation using free sugars and sulphuric acid immobilized on silica as catalyst. N-acetyl-d-glucosamine, N-acetyl-d-galactosamine, d-glucose, d-galactose, d-mannose, l-fucose, and lactose were glycosylated with propargyl alcohol or 2-azidoethanol affording the corresponding glycosides, with the production of the $\alpha$-glycopyranoside as the dominant product. Remarkable acceleration of the glycosylation reactions (15 min–2 h compared to several hours) over reported procedures together with good yields were always observed

Cite this Research Publication

Dr. Nasrin Shaikh, Russo, L., Cipolla, L., and Nicotra, F., “Ultrasonic assisted Fischer Glycosylation: Generating Diversity for Glycochemistry”, Molecular Diversity, vol. 15, pp. 341–345, 2011.

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