The novel coronavirus pandemic has spread over in 150 countries as of March 2020. Approximately 900,000 people have been infected so far (WHO COVID-19 report). The deadly scenario of COVID-19, started in the month of December 2019, was unraveling in Wuhan city of China and spread across the globe like a wildfire. In the month of January, WHO declared the outbreak as global emergency. Preventive measures are been taken globally to contain the rapid spread of virus. Compared to 2002 SARS epidemic, COVID-19 is apparently less lethal but far more contagious as it spreads more easily among individuals. Hence, in order to halt this human- to-human transmission chain, many preventive measures has been taken up. Currently, drug-based industry is reliant on chemical based drugs to treat viral infection which are known to initiate many side effects in human body. For this reason, natural sources need to be promoted that can act as a safe alternative to these drugs. This review highlights ongoing progress in figuring out the structure of major proteins designing vaccines and therapeutics to combat COVID-19 while also concentrating on developing preventive steps to avoid the emerging infection of viruses.
A. Shiva, Prasad, S., Karnataka, M., Shivamallu, C., Prasad, S., Begum, M., Gopinath, S., Srinivasa, C., Chennabasappa, L., and B, N., “Understanding the pathogen evolution and transmission prevention measures: Recent findings on molecular interventions towards COVID-19 therapeutics via hints from the past”, International Journal of Research in Pharmaceutical Sciences, pp. 975-7538, 2020.