Publication Type:

Journal Article

Source:

Journal of Applied Pharmaceutical Science, Volume 1, Number 4, p.97-99 (2011)

URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84875909269&partnerID=40&md5=f89984e8cea0417363743f0cf5713601

Abstract:

A simple, specific, rapid, precise and robust HPLC method has been developed for the quantitation of valsartan in tablet dosage form on a C18 column (250 x 4.6 mm) using a mobile phase consisting of ammonium dihydrogen phosphate buffer : methanol (33.5:66.5) adjusted to pH 3 with formic acid at a flow rate of 1.0 ml/min and detection at 265 nm. The retention time of valsartan was found to be at 11.9 min. The validation of above method was also done. Percentage label claim of the tablet formulations were found to be 100.8%. So the proposed method provides a faster and cost effective quality control tool for routine analysis of valsartan from formulations.

Notes:

cited By (since 1996)3

Cite this Research Publication

D. G. Ta Parambi, Mathew, Mb, and Ganesan, Vc, “A validated stability indicating HPLC method for the determination of Valsartan in tablet dosage forms.”, Journal of Applied Pharmaceutical Science, vol. 1, pp. 97-99, 2011.