Aeruginosa is an organism of interest for present day scientisys as it has evolved as a multidrug resistant organism and displays high environmental adaptability. Plant extracts play an essential role in treating various diseases. The threats in drug resistant pathogenic microbial stains can be prevented by the un-tapped medicinal principles from plants. Since P.aeruginosa is a multidrug resistant organism, it is important to develop new drugs to prevent its infections. In this study 10 plants were selected .These are Zingiber officinale, Maranta arundinaceae, Curcuma aromaticus, Allium oschaninni, Curcuma
domestica ,Allium cepa, Chromolaena odorrata, Aloe vera, Coleus aromaticus, Adothoda vasica. Aqueous extract of any of these plants shows antibacterial activity against this particular multidrug resistant strain.