Project Incharge: 
Dr. Asoke Banerji
Date: 
Sunday, March 1, 2009
School: 
School of Biotechnology
Funding Agency: 
Amrita Vishwa Vidyapeetham

Divergent oriented synthesis is a strategy which aims to the synthesis of compounds with diverse chemical structures. It is often an alternative to convergent synthesis or linear synthesis. With this intention, the diversity oriented synthesis was developed. In Phytochemistry laboratory our aims is to generate a library of bioactive oxygen heterocyclic compounds by first reacting with a easily available starting material to form set of intermediates, e.g. chalcones, 1,3-diketones.  The next target compounds are generated by suitable transformations of  intermediates, e.g. flavones, flavonols, flavanones, isoflavones and biflavones. This methodology quickly diverges to large numbers of different classes of compounds from simple starting materials. It is also efficient synthesis. The scheme methodology is given below.

diversity-bio-project

Some examples of  compounds synthesised are given below:

  1. chalcones
  2. dihydroflavonols
  3. flavones
  4. flavonol 
  5. isoflavones
207
PROGRAMS
OFFERED
6
AMRITA
CAMPUSES
15
CONSTITUENT
SCHOOLS
A
GRADE BY
NAAC, MHRD
8th
RANK(INDIA):
NIRF 2018
150+
INTERNATIONAL
PARTNERS