Project Incharge: 
Dr. Sudarslal S
Co-Project Incharge: 
Abhishek Nair A.
Akshay Iyer
Akshaya Balasubramanian
Prasanth Pillai P. R
Shankar Ganesh
Vijesh V
School: 
School of Biotechnology

Staphylococcus aureus is a gram-positive pathogen responsible for causing several infectious diseases and has been shown to be one of the leading causes of skin and soft tissue infections and bloodstream infections. The problem is further exacerbated by the development of antibiotic resistance. This necessitates the discovery of novel molecules showing anti-microbial activity against Methicillin-resistant Staphylococcus aureus (MRSA). The marine environment is taxonomically diverse with several possible sources of natural compounds. It also happens to be a relatively untapped and unexplored environment when compared to its terrestrial counterpart. Antimicrobial activities of marine algal extracts against several microorganisms have been reported. Yet the characterization and further investigation of responsible active principles has not been as widely explored. Based on these facts, we have decided to explore the possibility of discovering anti-MRSA compounds of marine algal extracts of as yet unexplored species and characterize the active principle responsible for the inhibitory activity using analytical techniques such as HPLC, TLC and mass spectrometry. In due course, we have observed an array of phenolic compounds, identified as phlorotannins, showed significant anti-MRSA properties, the structures of which are extensively characterized by different mass spectrometric techniques.

207
PROGRAMS
OFFERED
6
AMRITA
CAMPUSES
15
CONSTITUENT
SCHOOLS
A
GRADE BY
NAAC, MHRD
8th
RANK(INDIA):
NIRF 2018
150+
INTERNATIONAL
PARTNERS
  • Amrita on Social Media

  • Contact us

    Amrita Vishwa Vidyapeetham,
    Amritanagar,
    Coimbatore - 641 112,
    Tamil Nadu, India.
    • Fax                 : +91 (422) 268 6274
    • Coimbatore   : +91 (422) 268 5000
    • Amritapuri    : +91 (476) 280 1280
    • Bengaluru     : +91 (080) 251 83700
    • Kochi              : +91 (484) 280 1234
    • Mysuru          : +91 (821) 234 3479
    • Chennai         : +91 (44 ) 276 02165
    • Contact Details »