Project Incharge: 
Dr. Nandita Mishra
Co-Project Incharge: 
Dr. Asoke Banerji
Dr. Sanjay Pal
School: 
School of Biotechnology

Many cancer cells develop resistance to the apoptotic signals and flourish in the system. We are trying to target these defiant cells by inducing an alternative cell death pathway through natural products. One of the non-apoptotic mode of programmed cell death known as “paraptosis” or cytoplasmic vacuolation mediated cell death is one of our areas of interest.

We screen a large number of natural products and synthetic derivatives for anti-cancer activity in collaboration with Professor Asoke Banerji of School of Biotechnology and try to understand their mode of action with respect to cell death. Along with screening for anticancer compounds, we filter natural products that cause parasitic death. We are using C. elegans as an in vivo model system to study anti-parasitic and anti-cancer death mechanism in collaboration with Dr. Sanjay Pal.

207
PROGRAMS
OFFERED
6
AMRITA
CAMPUSES
15
CONSTITUENT
SCHOOLS
A
GRADE BY
NAAC, MHRD
8th
RANK(INDIA):
NIRF 2018
150+
INTERNATIONAL
PARTNERS