Project Incharge: 
Dr. Nandita Mishra
School: 
School of Biotechnology

The ubiquitin-proteasome system (UPS) plays an essential role in many cellular processes, including cell cycle progression, proliferation, apoptosis and angiogenesis. Proteasome inhibitors like Bortezomib (Velcade, PS-341), has been successfully used as anticancer drug. Several natural compounds, including the green tea polyphenols, microbial metabolite lactacystin and many triterpenes have been shown to be potent proteasome inhibitors. One of our ongoing project is to screen novel proteasomal inhibitors from natural products that induce cell death in cancer cells.

207
PROGRAMS
OFFERED
6
AMRITA
CAMPUSES
15
CONSTITUENT
SCHOOLS
A
GRADE BY
NAAC, MHRD
8th
RANK(INDIA):
NIRF 2018
150+
INTERNATIONAL
PARTNERS