• A Microbial Fuel Cell(MFC) or Biological fuel cell is a bioelectrochemical system that drives a current by using bacteria and mimicking bacterial interactions found in nature.Usually a microbial cell consists of two electrodes separated by a semi permeable membrane. The main objective of the present study was to work on different exoelectrogen and electrodes that could be more efficient and could be more efficient and could be cheaper than the existing ones.

    mfc-caulobactercrescentus-as-an-electrogen-in-a-dual-chambered-microbial-fuel-cell-with-the-novel-proton-exchange-membrane
  • Microfluidics is a multidisciplinary field which integrates physics, chemistry, biology, biotechnology, nanotechnology etc. We are focusing its mechanics as well as biological application in our project. Present work focuses on the behavior of biological macromolecules in a microfluidic device.

    morophological-evaluation-of-plasmid-dna-using-microfluidic-device
  • Aspergillusniger has the ability to produce Naringinase enzyme in a selective media under specific conditions. Naringinase has α-L-rhamnosidase and β-D-glucosidase activities. This hydrolytic enzymatic complex has wide occurrence in nature and has been reported in plants, yeasts, fungi and bacteria. Naringinase is commercially attractive due to its potential usefulness in pharmaceutical and food industries.

    production-purification-and-application-of-naringinase-from-aspergillussp-sec-nigri
  • Quantum dots, also known as nanocrystals, are a special class of materials known as semiconductors, which are crystals composed of periodic groups of II-VI, III-V, or IV-VI materials. Their size ranges from 2-10 nanaometers. At these small sizes materials behave differently, giving quantum dots unprecedented tunability and enabling never before seen applications to science and technology. They have properties that are between those of bulk semiconductors and those of discrete molecules.

    synthesis-and-characterization-of-lead-salt-based-linear-heterostructures-for-photovoltaic-applications
  • Endophytes/ endosymbionts from marine micro algae have recently gained attention as potential sources of bioactive secondary metabolites. Our aim is to isolate and identify the endophytes by molecular biology methods. 

    identification-of-endophytes-from-marine-algae-by-16s-rrna-sequencing
  • The role of various sugars on the surface glycans in bacterial /fungal pathogenesis of plants and animals is well known. The focus of our research group is to hit upon proteins which are capable of interacting with these sugars. A class of proteins called ‘’lectins” which are widely present in natural sources like plants, marine algae etc. are very specific in their interaction with various sugars/glycoproteins. The interactions will be studied by Isothermal Titration Calorimetry (ITC) and Surface Plasmon resonance (SPR). 

    marine-algae-an-important-source-for-lectins
  • Nowadays researchers are interested in cell patterning and here is a method used for patterning mammalian cells that does not require access to photolithographic capabilities. This work describes a versatile process for forming microstructures of polymers, ceramics and metals.

    mimic-a-unique-approach-to-wound-healing-assays
  • Diabetes is a long term prevailing disease which affects millions of people worldwide. It is a condition where the body fails to utilize the ingested glucose. There has been a dire need for the development of low cost yet effective glucose sensing device. Present day devices are amperometric and works on generated electrochemical signals.

    escherichia-coli-based-microfluidic-whole-cell-glucose-biosensor
  • Inflammation is the body's endeavor at self-defense, the intent being to eradicate harmful stimuli, including damaged cells, irritants, or pathogens and begin the healing process.  It is one of the major steps in normal wound healing process with overlapping events such as formation of granulation tissue, angiogenesis, and tissue remodeling. However, chronic inflammation can also lead to a host of diseases.

    regulation-of-inflammasomes-by-natural-product-extracts-role-in-metabolic-disorders
  • Poor sanitation contributes to 1.5 million child deaths globally from diarrhoea alone caused by enteric pathogens each year. Solving the sanitation challenge in the developing world will require radically new innovations that are deployable on a large scale. Hence, we aimed to reduce the bacterial load of waste water by developing bacteriophages from sewage against the enteric pathogens. Bacteriophages are the viruses which infect bacteria and kill them.

    isolation-of-bacteriophages-against-enteric-pathogens-from-sewage
  • Aspergillus sp. has the ability to produce Naringinase enzyme in a selective media under specific conditions. Naringinase has α-L-rhamnosidase and β-D-glucosidase activities. This hydrolytic enzymatic complex has wide occurrence in nature and has been reported in plants, yeasts, fungi and bacteria. Naringinase is commercially attractive due to its potential usefulness in pharmaceutical and food industries.

    production-purification-and-application-of-naringinase-from-soil-isolates-of-aspergillus-sp
  • Peptidoglycan (PG) hydrolases or autolysins are a group of enzymes which degrade bacterial cell wall at specific sites. Staphylococcus aureus produces two major PG hydrolases: major autolysin (Atl) and Aaa, a autolysin/adhesin protein. Amidase are surface-associated proteins that have both enzymatic and adhesive functions.

    expression-purification-and-refolding-of-recombinant-amidase-in-escherichia-coli

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