• Incomparison to the traditional biochemical tests, Ribotyping is a high throughput method that enables rapid identification of microorganisms. For the isolation of genomic DNA, conventional method of DNA extraction is used. The DNA thus extracted is PCR ready genomic DNA. This could be directly used for PCR without any purification step. PCR is done to amplify the gene. One set of universal primers were used for the amplification. After amplification, the PCR product was run on agarose gel.

    ribotyping-ribotyping-of-bacterial-endophytes
  • Diabetes is a long term prevailing disease which affects millions of people worldwide. It is a condition where the body fails to utilize the ingested glucose. There has been a dire need for the development of low cost yet effective glucose sensing device.

    escherichia-coli-based-microfluidic-whole-cell-glucose-biosensor
  • A Microbial Fuel Cell(MFC) or Biological fuel cell is a bioelectrochemical system that drives a current by using bacteria and mimicking bacterial interactions found in nature.Usually a microbial cell consists of two electrodes separated by a semi permeable membrane. The main objective of the present study was to work on different exoelectrogen and electrodes that could be more efficient and could be more efficient and could be cheaper than the existing ones.

    mfc-caulobactercrescentus-as-an-electrogen-in-a-dual-chambered-microbial-fuel-cell-with-the-novel-proton-exchange-membrane
  • The role of various sugars on the surface glycans in bacterial /fungal pathogenesis of plants and animals is well known. The focus of our research group is to hit upon proteins which are capable of interacting with these sugars. A class of proteins called ‘’lectins” which are widely present in natural sources like plants, marine algae etc. are very specific in their interaction with various sugars/glycoproteins. The interactions will be studied by Isothermal Titration Calorimetry (ITC) and Surface Plasmon resonance (SPR). 

    marine-algae-an-important-source-for-lectins
  • Quantum dots, also known as nanocrystals, are a special class of materials known as semiconductors, which are crystals composed of periodic groups of II-VI, III-V, or IV-VI materials. Their size ranges from 2-10 nanaometers. At these small sizes materials behave differently, giving quantum dots unprecedented tunability and enabling never before seen applications to science and technology. They have properties that are between those of bulk semiconductors and those of discrete molecules.

    synthesis-and-characterization-of-lead-salt-based-linear-heterostructures-for-photovoltaic-applications
  • Endophytes/ endosymbionts from marine micro algae have recently gained attention as potential sources of bioactive secondary metabolites. Our aim is to isolate and identify the endophytes by molecular biology methods. 

    identification-of-endophytes-from-marine-algae-by-16s-rrna-sequencing
  • Diabetes is a long term prevailing disease which affects millions of people worldwide. It is a condition where the body fails to utilize the ingested glucose. There has been a dire need for the development of low cost yet effective glucose sensing device. Present day devices are amperometric and works on generated electrochemical signals.

    escherichia-coli-based-microfluidic-whole-cell-glucose-biosensor
  • Nowadays researchers are interested in cell patterning and here is a method used for patterning mammalian cells that does not require access to photolithographic capabilities. This work describes a versatile process for forming microstructures of polymers, ceramics and metals.

    mimic-a-unique-approach-to-wound-healing-assays
  • Inflammation is the body's endeavor at self-defense, the intent being to eradicate harmful stimuli, including damaged cells, irritants, or pathogens and begin the healing process.  It is one of the major steps in normal wound healing process with overlapping events such as formation of granulation tissue, angiogenesis, and tissue remodeling. However, chronic inflammation can also lead to a host of diseases.

    regulation-of-inflammasomes-by-natural-product-extracts-role-in-metabolic-disorders
  • Lack of drinking water and proper sanitation are the major causes of enteric infection leading to huge malnutrition and other health problems in developing nations. Solving the sanitation challenge in the developing world will require radically new innovations that are deployable on a large scale. We aim to reduce the bacterial load of waste water by developing bacteriophages from sewage against the enteric pathogens. Bacteriophages are the viruses which infect bacteria and kill them.

    characterization-of-the-bacteriophages-binding-with-human-matrix-proteins
  • Bacillus clausii, a gram positive, spore forming bacteria is widely used a probiotic in preventing and treating various gastrointestinal disorders, are known to colonize in host systems. But Staphylococcus aureus, though gram positive and show ability to colonize in host systems, is pathogenic in nature.

    isolation-and-characterization-of-host-binding-proteins-from-bacillus-clausii-and-staphylococcus-aureus-using-mass-spectrometry-a-proteomic-approach
  • Poor sanitation contributes to 1.5 million child deaths globally from diarrhoea alone caused by enteric pathogens each year. Solving the sanitation challenge in the developing world will require radically new innovations that are deployable on a large scale. Hence, we aimed to reduce the bacterial load of waste water by developing bacteriophages from sewage against the enteric pathogens. Bacteriophages are the viruses which infect bacteria and kill them.

    isolation-of-bacteriophages-against-enteric-pathogens-from-sewage

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