• The project titled "Use of viral agents, microbial fuel cell and effec tive recycling strategy to improve the economics of human waste disposal" is funded by BIRAC & DBT, Govt. of India and The Bill & Melinda Gates Foundation. Dr. Bipin Nair is the Principal investigator of the project.

    use-of-viral-agents-microbial-fuel-cell-and-effec-tive-recycling-strategy-to-improve-the-economics-of-human-waste-disposal
  • Over the years, conjugation of bioactive molecules onto polymer matrices has emerged as a versatile strategy for a wide spectrum of applications including protein purification, waste water management, drug delivery, etc. In this work, we have explored the scope of employing chitosan the second most abundant biopolymer for protein purification via a facile bioconjugation protocol.

    schiff-s-base-derivative-of-chitosan-a-potential-matrix-for-metalloprotein-enrichment
  • Incomparison to the traditional biochemical tests, Ribotyping is a high throughput method that enables rapid identification of microorganisms. For the isolation of genomic DNA, conventional method of DNA extraction is used. The DNA thus extracted is PCR ready genomic DNA. This could be directly used for PCR without any purification step. PCR is done to amplify the gene. One set of universal primers were used for the amplification. After amplification, the PCR product was run on agarose gel.

    ribotyping-ribotyping-of-bacterial-endophytes
  • The role of various sugars on the surface glycans in bacterial /fungal pathogenesis of plants and animals is well known. The focus of our research group is to hit upon proteins which are capable of interacting with these sugars. A class of proteins called ‘’lectins” which are widely present in natural sources like plants, marine algae etc. are very specific in their interaction with various sugars/glycoproteins. The interactions will be studied by Isothermal Titration Calorimetry (ITC) and Surface Plasmon resonance (SPR). 

    marine-algae-an-important-source-for-lectins
  • Quantum dots, also known as nanocrystals, are a special class of materials known as semiconductors, which are crystals composed of periodic groups of II-VI, III-V, or IV-VI materials. Their size ranges from 2-10 nanaometers. At these small sizes materials behave differently, giving quantum dots unprecedented tunability and enabling never before seen applications to science and technology. They have properties that are between those of bulk semiconductors and those of discrete molecules.

    synthesis-and-characterization-of-lead-salt-based-linear-heterostructures-for-photovoltaic-applications
  • Endophytes/ endosymbionts from marine micro algae have recently gained attention as potential sources of bioactive secondary metabolites. Our aim is to isolate and identify the endophytes by molecular biology methods. 

    identification-of-endophytes-from-marine-algae-by-16s-rrna-sequencing
  • Diabetes is a long term prevailing disease which affects millions of people worldwide. It is a condition where the body fails to utilize the ingested glucose. There has been a dire need for the development of low cost yet effective glucose sensing device. Present day devices are amperometric and works on generated electrochemical signals.

    escherichia-coli-based-microfluidic-whole-cell-glucose-biosensor
  • Nowadays researchers are interested in cell patterning and here is a method used for patterning mammalian cells that does not require access to photolithographic capabilities. This work describes a versatile process for forming microstructures of polymers, ceramics and metals.

    mimic-a-unique-approach-to-wound-healing-assays
  • Inflammation is the body's endeavor at self-defense, the intent being to eradicate harmful stimuli, including damaged cells, irritants, or pathogens and begin the healing process.  It is one of the major steps in normal wound healing process with overlapping events such as formation of granulation tissue, angiogenesis, and tissue remodeling. However, chronic inflammation can also lead to a host of diseases.

    regulation-of-inflammasomes-by-natural-product-extracts-role-in-metabolic-disorders
  • The project titled "To strenthen the Post Graduate Teaching and Research Facilities in the department on 50:50 mode being a Private Academic Institution" is funded by FIST, Dept. of Science & Technology and Amrita Vishwa Vidyapeetham. Dr. Bipin Nair is the investigator of the project.

    to-strenthen-the-post-graduate-teaching-and-research-facilities-in-the-department-on-50-50-mode-being-a-private-academic-institution
  • Bacteriocins are antibacterial proteins produced by bacteria that can kill or inhibit the growth of other bacteria. Many lactic acid bacteria produce a high diversity of different bacteriocins. Many bacteriocins have been characterized biochemically or genetically and though there is a basic understanding of their structure, function, biosynthesis and mode of action, many aspects of these compounds are still unknown.

    isolation-partial-purification-and-characterisation-of-bacteriocins-from-fermented-foods
  • Malnutrition is a huge complex problem in developing nations with special reference to South Asia. Ethnically accepted fermented food and beverages, if designed properly, can potentially solve the problem in two ways: providing crucial nutrition and compete out the gut infection. We aim to develop probiotic strains from those food and drinks which are popular and economically affordable in Kerala.

    studies-on-probiotic-strains-from-fermented-foods

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