DETAILS: 

COURSE NAME: Bioinformatics 
COURSE CODE: BIF514
PROGRAM: 
M.Sc. Biotechnology 
SEMESTER: Three
CREDITS: Three
INSTRUCTOR: Asha Vijayan

SYLLABUS

  • Introduction to Bioinformatics:  Definition - Importance and uses of Bioinformatics- Information Technology- Systems Biology.
  • Bioinformatics Software: Clustal V - Clustal W 1.7- RasMol – Oligo – Molscript – Treeview – Alscript - Genetic Analysis Software- Phylip. Biocomputing: Introduction to String Matching Algorithms
  • Database Search Techniques- Sequence Comparison and Alignment Techniques- Use of Biochemical Scoring Matrices- BLAST and FASTA- Pairwise and Multiple sequence alignment. Profiles, motifs and features identification – Phylogenetics analysis
  • Introduction to Graph Matching Algorithms - Automated Genome Comparison and its Implication- Automated Gene Prediction- Automated Identification of Bacterial Operons and Pathways
  • Introduction to Signaling Pathways and Pathway Regulation. Gene Arrays - Analysis of Gene Arrays - Machine Learning Methods in Bioinformatics- Hidden Markov models- Applications of HMM in gene identification and Profiles HMMs- Neural Networks and Support Vector machines.
  • Matlab- Introduction to MATLAB commands,Introduction to arrays- indexing. R package- Statistical Analysis.Use R to analyze biological data.Introduction to internet and its application.