Cell Biology First Semester Syllabus for MSc Bioinformatics
COURSE NAME: Cell Biology
COURSE CODE: BIO421
PROGRAM: MSc Bioinformatics
Tools of cell biology. Ultra structure of prokaryotic and eukaryotic cells, organelles structure marker and function, Endoplasmic reticulum, Golgi complex, Types of vesicles - transport and their functions, Lysosomes. Nucleus - Internal organization, Nuclear pore complex, Nucleosomes Chromatin. Mitochondrial Genome, Structure and Function – Oxidative Metabolism in the Mitochondrion – The Role of Mitochondria in the formation of ATP – Translocation of Protons and the Establishment of a proton-motive force – The Machinery for ATP formation – Peroxisomes. Genome studies of Mitochondria. Chloroplast structure and function – An overview of photosynthetic Metabolism, Cytoskeleton – components of Cytoskeleton, Microtubules, Intermediate filaments – Microfilaments, Protein trafficking, Cell- to -Cell Signaling: Hormones and Receptors, Intracellular signaling in Development and Disease, Transport across Cell Membranes, Protein Sorting: Organelle Biogenesis and Protein secretion, Stem Cell Biology, Cancer, Regulation of Cell Death; Apoptosis, Circadian Rhythms.
- "Molecular Cell Biology” 5th Edition by Harvey Lodish, Arnold Berk, Paul Matsudaira, Chris Kaiser, Monty Krieger, Matthew Scott, Lawrence Zipursky and James Darnell. W.H Freeman and Company.
- The Cell A Molecular Approach-Cooper-Hausman
- Molecular Biology of the Cell- Bruce Alberts et al.