DETAILS: 

COURSE NAME: Developmental Biology
PROGRAM: M.Sc. Biotechnology and M.Sc. Microbiology 
SEMESTER: Three
CREDITS: Three
INSTRUCTOR:  SHALINI DINESH 

SYLLABUS

History & basic concepts of development : Overview of how the modern era of developmental biology emerged through multidisciplinary approaches, stages of development- zygote, blastula, gastrula , neurula, cell fate & commitment –  potency- concept of embryonic stem cells,  differential gene expression, terminal differentiation ,lineages of three germ layers, fate map, Mechanisms of differentiation-cytoplasmic determinants, embryonic induction,  concept of morphogen,  mosaic and regulative development, Pattern formation--   axis specification,   positional identification (regional specification), Morphogenetic movements, Model organisms          

 Early Development in invertebrate /vertebrate models  -Drosophila, C.elegans,   Xenopus,  Mouse/ human: Cleavage, gastrulation, Axis specification (Dorsoventral, anterior posterior), & body plan patterning,   left right asymmetry in vertebrates

Late Development in invertebrate /vertebrate models  :Organogenesis-  development of ectodermal organs, mesodermal organs, endodermal organs, vulval formation in C.elegans,

Germ cell specification& migration  

Overview of plant development

Medical implications of developmental biology -   genetic errors/ teratogenesis/ stem cell therapy etc

TEXT BOOKS

  1. Developmental Biology- Scott F Gilbert.
  2. Essential Developmental Biology - Jonathan Slack
  3. Principles of Development - Lewis Wolpert
  4. Developmental Biology,-Werner A Muller
  5. Website:   virtual embryo-  http://people.ucalgary.ca/~browder/virtualembryo/dev_biol.html