DETAILS: 

COURSE NAME: Microbial Physiology
COURSE CODE: MIC 402
PROGRAM:  M.Sc Microbiology
SEMESTER: One
CREDITS: Two
INSTRUCTOR:  Vidhya Prakash , Dr. Athira Omanakuttan

SYLLABUS:

  • Over view of prokaryotic cell- structure &functions Cell wall synthesis Membrane transport in bacteria-simple ,group   translocation , ABC transporters Protein export in bacteria –Type 1,2,3,4,  Protein export pathways  &  antimicrobial therapy Iron transport- siderophores   , Siderophores &  antimicrobial therapy
  • Bacterial cell shape - bacterial cytoskeleton, Cell division- molecular mechanisms involved in formation of Z-ring ,   Cell division machinery & antimicrobial therapy,
  • Two component signal transduction in prokaryotes--Chemotaxis  ,  Quorum sensing& biofilms ,   Quorum sensing & antimicrobial therapy  ,  Sporulation inducing signals & events in sporulation  ,  Osmolarity porin regulation in E.coli (Omp system) Phosphate assimilation in E.coli (Pho system) ,  Nitrogen fixation in Klebsiella& Rhizobium (Ntr system)
  • Stress physiology  --- effect of oxygen toxicity ,pH, osmotic pressure, heat shock etc on bacteria Adaptations in thermophiles, halophiles ,alkaliphiles ,acidophiles ,  Extremophiles – adaptations  & significance in biotechnology

 

REFERENCES

  • Microbial Physiology II edn, Moat, A.G. and Foster, J.W
  • Prescott, Harley, and Klein's Microbiology 8 th edition. Joanne M. Willey, Linda Sherwood, Christopher J. Woolverton. McGraw-Hill Higher Education

 

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