Details

COURSE NAME: Molecular Biology for Bioinformatics
COURSE CODE: BIO425
CREDIT: 3
SEMESTER: 1
PROGRAM: MSc Bioinformatics

Syllabus

Tools of molecular biology, Structure of Nucleic acids and proteins, DNA-Protein interactions, Transcription in prokaryotes, Control of prokaryotic transcription, Transcription in Eukaryotes, Post transcriptional events, Transcriptional regulation, Translation and translational regulation, post translational modification, RNA and Protein export and its regulation. DNA Replication and enzymology, DNA damage and repair. Noncoding RNA, transposons. Introduction to Genomics, Proteomics, Metabolomics. evidence for DNA as genetic material. Gene transfer in microorganisms – conjugation, transformation, transduction - protoplasmic fusion. The genomes of bacteria, viruses, plasmids. Introduction to the methods of DNA sequencing.

Textbooks

1. The Cell A Molecular Approach-Cooper-Hausman
2. Molecular biology by Rober F. Weaver

Reference Books

  1. Molecular biology of Genes by James Watson 
  2. Molecular biology by David Freifelder 
  3. Molecular Biology of the Cell- Bruce Alberts et al.