COURSE NAME: Structural Bioinformatics
COURSE CODE: BIF409
PROGRAM: MSc Bioinformatics
Fundamentals of protein, DNA, RNA structure, macromolecular structure determination, X ray crystallography, NMR spectroscopy, Electron microscopy, Structure formats, molecular visualization, Protein structure evolution and SCOP database, CATH domain structure database, identifying structural domains in protein, prediction of protein - protein interaction from phylogenetic analysis, structure comparison and alignment, structural bioinformatics in drug discovery, CASP and CAFASP experiments, homology modeling, fold recognition methods, AB INITIO methods. Secondary structure prediction.