DETAILS:

COURSE NAME: Structural Bioinformatics
COURSE CODE: BIF409
CREDIT: 4
SEMESTER: 2
PROGRAM: MSc Bioinformatics

SYLLABUS

Fundamentals of protein, DNA, RNA structure, macromolecular structure determination, X ray crystallography, NMR spectroscopy, Electron microscopy, Structure formats, molecular visualization, Protein structure evolution and SCOP database, CATH domain structure database, identifying structural domains in protein, prediction of protein - protein interaction from phylogenetic analysis, structure comparison and alignment, structural bioinformatics in drug discovery, CASP and CAFASP experiments, homology modeling, fold recognition methods, AB INITIO methods. Secondary structure prediction.

TEXT BOOKS

  1. Structural bioinformatics, Philip E Bourne, HelgeWeisssig
  2. Protein Bioinformatics : An Algorithmic Approach to Sequence and Structure Analysis by Ingvar Eidhammer, et al;