Research is an integral component of dental education. Considering this, much emphasis is given for research right from the undergraduate level.

The School has initiated a number of substantive developments to support the research endeavor and to demonstrate our commitment to support research in the faculty.

The programs offered are focused on a wide range of areas including Conservative Dentistry & Endodontics, Oral & Maxillofacial Pathology & Microbiology, Oral & Maxillofacial Surgery, Oral Medicine and Radiology, Orthodontics & Dentofacial Orthopedics, Paediatric Dentistry, Periodontics, Prosthodontics, Public Health Dentistry.

Quality, innovative and value based research is much encouraged and the school has started taking heights in research achievements.

It is what distinguishes us from similar schools and what equip our students for leading - edge positions on the rapidly changing healthcare frontier.

Research Projects

a) Improving the Dental Implant Tissue Bonding by Nano Texture - A Cost Effective Approach -  Dr. Anil Mathew

To study the development of dental implants that show faster and enhanced osseointegration, less technique sensitive and which can be used in compromised conditions like diabetes mellitus, osteoporosis, etc.

b) Clinical Application of Tissue Engineering for Bone Augmentation and Endosseous Dental Implants - Dr. Manju V.

This research is mainly focused on clinical use of tissue engineered bone substitute for augmentation of resorbed alveolar ridges and surgically reconstructed maxillectomy and mandibulectomy defects.
 

Contemplating Projects
1. Estimation of Titanium residue around Hydrothermally Nano Textured Titanium Dental Implant-an ex-vivo study in Pig Mandible, Dr. Anil Mathew, Dr. Rahul Ravindran
2. Evaluation of Correlation between Skin colour and Tooth colour in Dentulous patients, Dr. Anil Mathew, Dr. Neena George
3. Patient Satisfaction and Quality of Life and Denture Efficiency in patients of Amrita school of dentistry and Amithasmitham which is a Tribal outreach programme, Dr. Anil Mathew, Dr. Albin Geo Joseph
4. An Assessment of Distribution of Edentulous Spaces in Patients of Partial Edentulism Reporting for Treatment in the Department of Prosthodontics, Dr. Tony Thomas, Dr. R. Sreeraj
Ongoing Projects 
1. Comparative Study of Alveolar Ridge Augmentation Beyond the Confines of Existing Socket Walls Using different forms of Plasma Rich Fibrin Matrix, Dr. Haripriya E. C., Department of Prosthodontics
2. Adhesion of Actinobacillus Actinomycetumcomitance on different surface modifications of Titanium-an invitro study, Dr. Rahul Ravindran, Department of Prosthodontics
3. Comparison of Functional outcomes in Surgically and Prosthetically Rehabilitated Maxillectomy patients, Dr. R. Sreeraj, Department of Prosthodontics
4. Estimation of Prosthetic status and Prosthetic needs in the elderly in the municipal wards of Aluva ,Cochin, Kerala, Dr. Albin Geo Joseph, Department of Prosthodontics
5. Effect of Chemical Disinfectants and Accelerated aging on Maxillofacial Silicones, Dr. Anna Serene Babu, Department of Prosthodontics
6. Comparison of Radiation dose distribution with and without Tissue equivalent Prosthetic material in external auditory canal, Dr. Tharangini Madhusudhanan, Department of Prosthodontics
7. Improving the dental implant tissue bonding by Nano texture- A cost effective approach, Dr. Anil Mathew, Concept proposal accepted by ICMR
8. Clinical Application of Tissue Engineering for Bone Augmentation and Endosseous dental implants, Dr. Manju V.
Projects Completed   
1. Comparative Evaluation of the efficacy of Occlusal splints fabricated in different mandibular positions for treatment in Temporomandibular Disorder Patients, Dr. Ipe Sabu, Department of Prosthodontics
2. Estimation of Cytokine level in gingival crevicular fluid using three different Gingival Retraction systems in patients requiring fixed partial denture, Dr. Liji Mathew, Department of Prosthodontics
3. Relationship of choice of tooth color with the skin color of edentulous patients, Dr. Neena George, Department of Prosthodontics
4. Alveolar Bone Defect and Secondary Bone Grafting Outcome in Cleft Lip/Palate Patients, Dr. Alice Kurian, Dr. Ravi, Department of Periodontics
5. Analyzing the outcome of Mandibular Ameloblastoma reconstructed with fibula free flap, Dr. Reesma, Department of Periodontics, Collaboration with Head & Neck Department AIMS
6. Comparison of TIMP-1 levels in periodontally involved and healthy controls and its response to non-surgical periodontal therapy, Dr. Maya, Dr. Angel, Department of Periodontics, Collaboration with Dept of Biochemistry – CMC Vellore
7. Relationship between life - event stress and Periodontal disease and its response to treatment, Dr. Saimegha, Dr. Jayachandran, Department of Periodontics
8. Comparison of efficacy of Hand Instruments, Ultrasonic Instruments and lasers on root surface debridement – An in-vitro study, Dr. Neha, Dr. Jayachandran, Department of Periodontics, Collaboration with Sree Chithra Thirunal Institute of Medical Sciences & technology, TVM and Cochin university of Science and Technology
9. Comparison of the Efficacy of Iontophoresis with APF Gel and Desensitizing Tooth paste in the management of Dentinal Hyper sensitivity, Dr. Keerthy, Dr. Jayachandran, Department of Periodontics, Collaboration with Dept of Oral Medicine and Radiology

Publications

Year of Publication Publication Type Title

2019

Journal Article

D. Mary Sam, Kumar, S. P., Varma, B., David, A. P., and Suresh, R., “Benign osteoblastoma of the palate: a rare clinical presentation.”, Oral Radiol, 2019.[Abstract]


Osteoblastoma is a rare, benign type of osteoblastic tumor. It constitutes approximately 1% of all primary bone tumors. Osteoblastoma most commonly affects the long bones; it very rarely affects the jaw bones. Because of its clinical and histological similarity with other bony tumors, such as osteoid osteoma and fibro-osseous lesions, osteoblastoma is a diagnostic challenge. Very few cases of osteoblastoma involving the maxillofacial region have been reported to date. We herein describe a 15-year-old female patient with osteoblastoma that presented as a palatal swelling of 6 months' duration.

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2019

Journal Article

R. D. Prabha, Nair, B. P., Ditzel, N., Kjems, J., Nair, P. D., and Kassem, M., “Strontium functionalized scaffold for bone tissue engineering.”, Mater Sci Eng C Mater Biol Appl, vol. 94, pp. 509-515, 2019.[Abstract]


Drug functionalized scaffolds are currently being employed to improve local delivery of osteoprotective drugs with the aim of reducing their loading dose as well as unwanted systemic complications. In this study we tested a poly-(ε) caprolactone (PCL)-laponite-strontium ranelate (SRA) composite scaffold (PLS3) for its abilities to support growth and osteogenic differentiation of human marrow derived stromal stem cells (hMSC). The in vitro experiments showed the PLS3 scaffold supported cell growth and osteogenic differentiation. The in vivo implantation of hMSC seeded PLS3 scaffold in immunocompromised mice revealed vascularized ectopic bone formation. PLS3 scaffolds can be useful in bone regenerative applications in the fields of orthopaedics and dentistry.

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2019

Journal Article

A. Aiswarya, Suresh, R., Janardhanan, M., Savithri, V., Aravind, T., and Mathew, L., “An Immunohistochemical Evaluation of Podoplanin Expression in Oral Leukoplakia and Oral Squamous Cell Carcinoma to Explore its Potential to be used as a Predictor for Malignant Transformation.”, J Oral Maxillofac Pathol, vol. 23, no. 1, p. 159, 2019.[Abstract]


<p><b>Background: </b>Oral leukoplakia (OL) is a potentially malignant disorder with increased risk for the development of oral squamous cell carcinoma (OSCC). Many cases of OSCC arise from the malignant transformation of preexisting OL. However, the risk of progression into OSCC and the possible prediction of malignant potential of OL remain inconclusive. Recent studies have shown that podoplanin, a mucin-like transmembrane glycoprotein specifically expressed in lymphatic endothelial cells, is expressed in various neoplasms including OSCC, indicating its possible biologic role in tumor cells. In this study, an evaluation of podoplanin expression in OL and OSCC has been carried out to assess its potential role as a biomarker to predict the possibility of malignant transformation in OL cases.</p>

<p><b>Aims and Objectives: </b>To assess the usefulness of podoplanin as a potential biomarker for predicting the risk of malignant transformation in OL, by comparing its immunohistochemical expression in OL and OSCC.</p>

<p><b>Materials and Methods: </b>Archival paraffin-embedded blocks of 25 OL cases with varying grades of dysplasia and 30 OSCC cases showing its varying grades were selected. Sections were subjected to immunohistochemical staining for podoplanin and compared with the control group for evaluation of results in the three groups.</p>

<p><b>Results: </b>A statistically significant increase in podoplanin expression was observed from normal mucosa through OL to OSCC. In the OL cases, the podoplanin staining score progressively increased from mild dysplasia to carcinoma , whereas in OSCC, well-differentiated group showed the maximum expression of podoplanin.</p>

<p><b>Conclusion: </b>The progressive increase in podoplanin expression through the increasing grades of dysplasia in OL is suggestive of an increased risk for malignant transformation with increased expression of podoplanin in OL cases. A high podoplanin expression in the well-differentiated OSCC may indicate a vital role for podoplanin in the early stages of tumorigenesis.</p>

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2019

Journal Article

V. Sanjeevan, Chandrashekar Janakiram, and Joseph, J., “Effectiveness of School-based Dental Screening in Increasing Dental Care Utilization: A Systematic Review and Meta-Analysis”, Indian J Dent Res, vol. 30, no. 1, pp. 117-124, 2019.[Abstract]


Background: School based dental screening has been a popular public health intervention. However, literature provides contrasting evidence regarding effectiveness of such programs on the utilization of dental services.

Objectives: We designed this review to understand the differences in dental attendance rates of children below 15 years of age, receiving a school based dental screening versus those not receiving it.

Material and Methods: The standard methodological procedures prescribed by The Cochrane Collaboration for Systematic review and meta-analysis was employed. An electronic (MEDLINE via PUBMED, Cochrane trial registry, and Google scholar) and a manual search (2016) were made to identify studies.

Results: Five studies met the inclusion criteria, covering a population of 28208 school children of which 21447 were included in the meta-analysis. The review concludes that school based dental screening marginally increases the dental attendance by 16 percent as opposed to a non-screening group (RR 1.16 (95% CI 1.11, 1.21). The quality of evidence was found to be low.

Conclusions: There is evidence of marginally increased dental attendance rate of 16 % following screening. As the quality of evidence was found to be low, the results of this review may be used with caution.

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2019

Journal Article

M. Janardhanan, Suresh, R., Savithri, V., and Veeraraghavan, R., “Extranodal Diffuse Large B Cell Lymphoma of Maxillary Sinus Presenting as a Palatal Ulcer”, BMJ Case Rep, vol. 12, no. 2, 2019.[Abstract]


A multitude of disease processes ranging from periodontitis to malignancies can lead to formation of solitary ulcer on the palate. Hence solitary ulcers of palate can often be a challenging one to diagnose. We report an interesting case of a diffuse large B cell lymphoma of the maxillary sinus which perforated the palatal bone and presented clinically as a palatal ulcer. Initially the lesion manifested as a small ill-defined swelling in the posterior palatal slope in relation to 24and25 which were mobile and hence was erroneously diagnosed as chronic periodontal abscess. This paper is intended to stress the relevance of including non-Hodgkin's lymphoma in the differential diagnosis of solitary palatal ulcers as it may be often misdiagnosed as more common reactive or inflammatory lesions.

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2019

Journal Article

Sreekumar P., Kumaran P., Arun Mamachan Xavier, Dr. Balagopal Varma R., and Kumar S. J., “Qualitative and quantitative comparison of the remineralization potential of three suitable materials – An in-vitro SMH & SEM study”, J ClinDiag Res , vol. 13, no. 1, pp. ZC01-ZC04, 2019.

2019

Journal Article

Sathish A. M., Arun Mamachan Xavier, Dr. Balagopal Varma R., Kumaran P., and Menon M. M., “Dental age assessment in 8-16 year old girls in a tertiary care hospital in Cochin – a comparative study”, Drug Inv Today , vol. 11, no. 4, pp. 996-999, 2019.[Abstract]


Introduction: Age determination plays a great role in forensic medicine, pediatric endocrinology, and pedodontic treatment planning. It helps in the management of different types of malocclusion in relation to maxillofacial growth. The aim of the study was to determine the dental developmental stages in female population and to test the applicability of Demirjian’s and Nolla’s criteria for maturity scoring in dental age assessment. Materials and Methods: Orthopantomographs of 200 females of 8–16 years were taken and the dental age was calculated using the Demirjian’s and Nolla’s dental age estimation method. Chronological age was also recorded and correlated to the dental ages obtained. Results: A strong correlation was found between chronological and dental ages (P < 0.005). The intraclass correlation coefficient between the two methods showed excellent agreement between the two (P < 0.005). Conclusion: A positive high degree correlation noticed between chronological age, dental age, and both age estimation methods may thus be applicable to the female population in Cochin.

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2019

Journal Article

Resmy Nair, Parvathy Kumaran, Arun Mamachan Xavier, and Dr. Balagopal Varma R., “Knowledge, attitude, and awareness of mothers toward emergency management of dental trauma in high literacy population”, J Int Oral Health, no. 11, pp. 287-292, 2019.

2019

Journal Article

Abraham B., Kumaran P., Arun Mamachan Xavier, Dr. Balagopal Varma R., and Kumar S. J., “Comparative evaluation of the efficacy of Aloe Vera gel with milk and HBSS in maintaining the viability of PDL cells in avulsed teeth”, Drug Inv Today , vol. 11, no. 4, pp. 996-999, 2019.

2018

Journal Article

S. Vellappally, Kheraif, A. A. Al, Anil, S., Assery, M. K., K Kumar, A., and Divakar, D. Devang, “Analyzing Relationship between Patient and Doctor in Public Dental Health using Particle Memetic Multivariable Logistic Regression Analysis Approach (MLRA2).”, J Med Syst, vol. 42, no. 10, p. 183, 2018.[Abstract]


In the developing technology managing patient and doctor relationship and communication process is one of the critical factors because the patient may take high risk surgery, treatment and diagnosis. Due to the importance of the patient-doctor relationship, in this paper investigate the various aspects of relation between the doctor and dental problem related patients. During the analyzing process, data has been collected from adults who are facing dental problems and other dental injuries in which data has been gathered from 423 individuals by conducting interviews. The gathered data is investigated with the help of particle-memetic multivariable logistic regression analysis method which examines the patient income, dental surgical details, injuries and other factors relationship has been investigated. From the analyzed data, how the patients are treated by doctors examined for improving the relationship between patient and doctor in public dental health aspects.

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BOOKS

book1

Orban’s Oral Histology and Embryology
Dr. Vinodkumar R. B.
13 Edition
2011

book2

Text book of Dental Radiology
Dr. Pramod John
Jaypee Medical Book Publishers
2010

book3

Textbook of Oral Medicine
Dr. Pramod John
JP Publishers
2005

book4

Textbook of Oral Medicine
Dr. Pramod John
JP Publishers
2005