Dr. Indulekha C. L. Pillai, Assistant Professor, Amrita School of Biotechnology, Amritapuri, has been awarded the prestigious Ramalingaswami Fellowship from the Department of Biotechnology, Government of India, on 15th November 2017, for a period of 5 years.

Dr. Shyam Diwakar, Director, Computational Neuroscience and Neurophysiology and Associate Professor, Amrita School of Biotechnology, Amritapuri, was an invited speaker for the third time at an event organised by the International School of Brain Cells & Circuits.  

Amrita Computational Neuroscience & Neurophysiology Lab recently developed a ‘Narrative Construct Sequence Learning’ method based on human capability towards narration of stories. The method was evaluated in the context of online systems. 

An international​ workshop and paper session on bio inspired modeling and computational neuroscie

Year of Publication Publication Type Title

2018

Journal Article

C. Porayath, Veedu, A. P., Babu, P., Dr. Bipin G. Nair, Madhavan, A., and Dr. Sanjay Pal, “Autolysin mediated adherence of Staphylococcus aureus with Fibronectin, Gelatin and Heparin”, International Journal of Biological Macromolecules, 2018.

2018

Journal Article

P. Somanath, Bush, K. M., and Knoepfler, P. S., “ERBB3-Binding Protein 1 (EBP1) Is a Novel Developmental Pluripotency-Associated-4 (DPPA4) Cofactor in Human Pluripotent Cells”, STEM CELLS, p. n/a–n/a, 2018.[Abstract]


Developmental Pluripotency-Associated-4 (DPPA4) is one of the few core pluripotency genes lacking clearly defined molecular and cellular functions. Here, we used a proteomics screening approach of human embryonic stem cell (hESC) nuclear extract to determine DPPA4 molecular functions through identification of novel cofactors. Unexpectedly, the signaling molecule ERBB3-binding protein 1 (EBP1) was the strongest candidate binding partner for DPPA4 in hESC. EBP1 is a growth factor signaling mediator present in two isoforms, p48 and p42. The two isoforms generally have opposing functions, however their roles in pluripotent cells have not been established. We found that DPPA4 preferentially binds p48 in pluripotent and NTERA-2 cells, but this interaction is largely absent in non-pluripotent cells and is reduced with differentiation. The DPPA4–EBP1 interaction is mediated at least in part in DPPA4 by the highly conserved SAF-A/B, Acinus and PIAS (SAP) domain. Functionally, we found that DPPA4 transcriptional repressive function in reporter assays is significantly increased by specific p48 knockdown, an effect that was abolished with an interaction-deficient DPPA4 ΔSAP mutant. Thus, DPPA4 and EBP1 may cooperate in transcriptional functions through their physical association in a pluripotent cell specific context. Our study identifies EBP1 as a novel pluripotency cofactor and provides insight into potential mechanisms used by DPPA4 in regulating pluripotency through its association with EBP1. Stem Cells 2018

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2017

Journal Article

Asha Vijayan, Chaitanya Nutakki, Dhanush Kumar, Dr. Krishnashree Achuthan, Dr. Bipin G. Nair, and Dr. Shyam Diwakar, “Enabling a freely accessible open source remotely controlled robotic articulator with a neuro-inspired control algorithm”, International Journal of Interactive Mobile Technologies, vol. 13, no. 1, pp. 61-75, 2017.[Abstract]


Internet-enabled technologies for robotics education are gaining importance as online platforms facilitating and promoting skill training. Understanding the use and design of robotics is now introduced at university undergraduate levels, but in developing economies establishing usable hardware and software platforms face several challenges like cost, equipment etc. Remote labs help providing alternatives to some of the challenges. We developed an online laboratory for bioinspired robotics using a low-cost 6 degree-of-freedom robotic articulator with a neuro-inspired controller. Cerebellum-inspired neural network algorithm approximates forward and inverse kinematics for movement coordination. With over 210000 registered users, the remote lab has been perceived as an interactive online learning tool and a practice platform. Direct feedback from 60 students and 100 university teachers indicated that the remote laboratory motivated self-organized learning and was useful as teaching material to aid robotics skill education.

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2017

Book Chapter

Dr. Shyam Diwakar, Medini, C., Nair, M., Parasuram, H., Asha Vijayan, and Dr. Bipin G. Nair, “Computational Neuroscience of Timing, Plasticity and Function in Cerebellum Microcircuits”, in Computational Neurology and Psychiatry, vol. 6, Springer Series in Bio-/Neuroinformatics, 2017, pp. 343–371.[Abstract]


Cerebellum has been known to show homogeneity in circuit organization and hence the “modules” or various circuits in the cerebellum are attributed to the diversity of functions such as timing, pattern recognition, movement planning and dysfunctions such as ataxia related to the cerebellum. Ataxia-like conditions, induced by intrinsic excitability changes, disable spiking or bursts and thereby limit the quanta of downstream information. Understanding timing, plasticity and functional roles of cerebellum involve large-scale and microcircuit reconstructions validating molecular mechanisms in population activity. Using mathematical modelling, we attempted to reconstruct information transmission at the granular layer of the cerebellum, a circuit whose role in dysfunctions remain yet to be fully explored. We have employed spiking models to reconstruct timing roles and detailed biophysical models for extracellular activity and local field population response. The roles of inhibition, induced plasticity and their implications in information transmission were evaluated. Modulatory roles of Golgi inhibition and pattern abstraction via optimal storage were estimated. An abstraction of the granular and Purkinje layer circuit for neurorobotic roles such as pattern recognition and spike encoding via two new methods was developed. Simulations suggest plasticity at cerebellar relays may be an important element of tremendous storage capacity reliable in the learning of coordination of actions, sensorimotor or cognitive, in which the cerebellum participates. More »»

2017

Journal Article

M. Dammalli, Murthy, K. R., Pinto, S. M., Murthy, K. Babu, Nirujogi, R. Sekhar, Madugundu, A. K., Dey, G., Dr. Bipin G. Nair, Gowda, H., and Prasad, T. Subrahmany, “Toward Postgenomics Ophthalmology: A Proteomic Map of the Human Choroid-Retinal Pigment Epithelium Tissue.”, OMICS, vol. 21, no. 2, pp. 114-122, 2017.[Abstract]


Ophthalmology and visual health research have received relatively limited attention from the personalized medicine community, but this trend is rapidly changing. Postgenomics technologies such as proteomics are being utilized to establish a baseline biological variation map of the human eye and related tissues. In this context, the choroid is the vascular layer situated between the outer sclera and the inner retina. The choroidal circulation serves the photoreceptors and retinal pigment epithelium (RPE). The RPE is a layer of cuboidal epithelial cells adjacent to the neurosensory retina and maintains the outer limit of the blood-retina barrier. Abnormal changes in choroid-RPE layers have been associated with age-related macular degeneration. We report here the proteome of the healthy human choroid-RPE complex, using reverse phase liquid chromatography and mass spectrometry-based proteomics. A total of 5309 nonredundant proteins were identified. Functional analysis of the identified proteins further pointed to molecular targets related to protein metabolism, regulation of nucleic acid metabolism, transport, cell growth, and/or maintenance and immune response. The top canonical pathways in which the choroid proteins participated were integrin signaling, mitochondrial dysfunction, regulation of eIF4 and p70S6K signaling, and clathrin-mediated endocytosis signaling. This study illustrates the largest number of proteins identified in human choroid-RPE complex to date and might serve as a valuable resource for future investigations and biomarker discovery in support of postgenomics ophthalmology and precision medicine.

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2017

Journal Article

A. Ma HimaVyshnavi, Anand, C. Lb, Deepak, O. Mc, and P. K. Krishnan Namboori, “Evaluation of colorectal cancer (CRC) epidemiology a pharmacogenomic approach”, Journal of Young Pharmacists, vol. 9, pp. 36-39, 2017.[Abstract]


Background: The population-wise variation in proneness of Colorectal Cancer (CRC) has been studied in the manuscript. A population wise analysis of responsiveness towards colorectal cancer is carried out with genetic, epigenetic, metagenomic and environmental factors associated with APC mutation mainly responsible for CRC among eight different populations. Methods and Material: The APC mutation has been obtained using the 'human gene mutation database-HGMD' and the 'international cancer genome consortium-ICGC' Data Portal. The epigenetic factors affecting colon cancer have been identified through EpiGRAPH tool. The 'human oral microbiome database (HOMD) and 'comparative toxicogenomics database (CTD)' are used to find the metagenomic factors affecting CRC. Results: Variants of APC gene from the selected ethnic classes chosen from Argentina, France, Germany, India, Poland, Romania, UK and USA were characterized, where the chromosome positions 112102966-112177228 are found to be affected. It has been found that among epigenetic factors: chromosome organization, population variation, and evolutionary history are highly promising features for the prediction of DNA methylation. It has been found that consumption of linoleic acid, oleic acid, and lauric acid play a major role in preventing CRC. Conclusions:The chromosome positions 112102966-112177228 are found to be the most prone region for APC mutation. Chromosome organization, population variation, and evolutionary history are highly promising epigenetic features for the prediction of DNA methylation and further mutation. The consumption of spices, coconut oil, fish (in coastal areas), dairy products and reduced intake of red meat may be the reasons for less incidence rate of CRC among the Indian population.

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2017

Journal Article

J. Raveendran, P.E., R., Dr. Ramachandran T., Dr. Bipin G. Nair, and Dr. Satheesh Babu T. G., “Fabrication of a disposable non-enzymatic electrochemical creatinine sensor”, Sensors and Actuators B: Chemical, vol. 243, pp. 589 - 595, 2017.[Abstract]


Abstract A disposable non-enzymatic sensor for creatinine was developed by electrodepositing copper on screen printed carbon electrodes. The sensor was characterized using electrochemical and microscopic techniques. Electrochemical detection of creatinine was carried out in phosphate buffer solution of pH 7.4. The estimation was based on the formation of soluble copper-creatinine complex. The formation of copper-creatinine complex was established using the pseudoperoxidase activity of copper-creatinine complex. The sensor showed a detection limit of 0.0746 μM with a linear range of 6–378 μΜ. The sensor exhibited a stable response to creatinine and found to be free from interference from molecules like urea, glucose, ascorbic acid and dopamine. Real sample analysis was carried out with blood serum.

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2017

Journal Article

C. R. Reshmi, Menon, T., Binoy, A., Dr. Nandita Mishra, Elyas, K. K., and Sujith, A., “Poly(L-lactide-co-caprolactone)/collagen electrospun mat: Potential for wound dressing and controlled drug delivery”, International Journal of Polymeric Materials and Polymeric Biomaterials, vol. 66, no. 13, pp. 645-657, 2017.[Abstract]


Here we report a novel bioactive electrospun mat based on poly(L-lactide-co-caprolactone) (PLLC) and collagen for wound dressing and sustained drug delivery of gentamicin. PLLC/collagen electrospun mat loaded with 10% gentamicin showed bioactivity for 15 days against Gram-positive and Gram-negative bacteria. The in vitro cell culture of 3T3 fibroblasts confirmed that these electrospun mat provide an increased specific interface area and hydrophilicity to enhance cell attachment, proliferation, and migration. The modified PLLC/collagen mat provided an excellent enhancement in properties of antibacterial wound dressings with a minimum in vitro toxicity and high potency for promoting wound healing stages. © 2017 Taylor & Francis.

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Viral agents to target and kill pathogens and odour-producing bacteria in fecal waste

Viruses infecting the bacteria, called bacteriophage (phage), have been used for over 90 years as an alternative to antibiotics in Russia, east Europe and France.  They are currently being tried as a possible therapy against multi-drug-resistant

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Designing a BMI-based robotic arm using EEG and motor articulation control

In this project, we will use EEG recordings to control robotic arm by extracting left and right side motor imagery movement patterns. We will develop and use feature extraction methods to extract the required features from the pre-processed

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Identification of Molecular Mechanisms of Action of the Cardioprotective Compound Arjunolic Acid

Anthracyclines are among the most effective anti-cancer treatments ever developed, but their clinical use is limited by their cumulative dose-related cardio-toxicity which may ultimately lead to a severe form of cardiomyopathy.

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Molecular Mechanisms in Impaired Wound-Healing

Diabetic wound healing is a challenging problem to solve as it requires the integration of interdependent processes that involve signal transduction input from inflammation, cell migration, cell proliferation,

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Quorum Sensing and Biofilm Formation in Microbial Pathogenesis

When encountering a new host, every potential microbial pathogen can stay, acquire nutrients, colonize and then seek another host.  Alternatively the pathogen could express its full battery of virulence factors, and invade the host.

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An innovative green technology for treating municipal and industrial wastewater entering rivers and...

This research project seeks to bring together biomass based biochars and hydrochars from rice husk waste product to remove heavy metals and other contaminants from industrial and domestic wastewater that makes its way untreated or only partially

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Development and Fabrication of non-enzymatic Electrochemical Glucose Biosensor and Fabrication of...

Diabetes mellitus is a public health problem affecting millions of people worldwide. Commercially available glucose sensors are enzyme based and has serious drawbacks like insufficient long-term stability, which originates from the intrinsic

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The Discovery of MicroRNAs (miRNAs) that Regulate the Expression of Gelatinase A (Matrix...

MicroRNAs (miRNAs) are short double stranded RNAs that are produced endogenously in mammalian cells, and control the regulation of many target genes at the post-transcriptional level. There are many reports of the misregulation of these miRNAs in

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Development of chromatographic separation and detection techniques for natural products, as plant...

The separation and characterization of bioactive compounds from plant extract is the crucial step in the study of phytochemicals.

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Affordable paper based microfluidics point of care testing device for liver function

Liver function test is one of the commonly performed blood analyses. Colorimetric test for the estimation of liver enzymes and total proteins are well established. The objective of this project is to integrate all the colorimetric tests into a

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Seabuckthorn – A Repository of Bioactive Phytochemicals

Seabuckthorn (SBT), (Hippophae L.) are deciduous shrubs in the genus Hippophae, family Elaeagnaceae.

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Natural products as modulators of diabetes associated endothelial dysfunctions

Endothelium helps in maintaining vascular tone by regulating the vascular permeability. It selectively allows only certain molecules to cross the endothelial barrier.

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Escherichia Coli based microfluidic whole-cell glucose biosensor

Diabetes is a long term prevailing disease which affects millions of people worldwide. It is a condition where the body fails to utilize the ingested glucose. There has been a dire need for the development of low cost yet effective glucose

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Value Addition to Underutilized Biosources

There are a wide range of underutilized plants with well known nutritional and medicinal properties. They have the potential for further promotion as they are locally available or are byproducts or waste materials.

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Cerebellum Inspired Approach for Pattern Classification in Robots

This project proposes to develop a cerebellum inspired pattern recognition algorithm for robotic data classification.

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Lentiviral Vectors for the Creation of Transgenic Organisms

Lentiviral vectors are powerful tools to deliver genetic material into almost any cell or tissue, and are useful even in the creation of transgenic animals. They have been shown to deliver foreign genes not only to mammalian cells, but also in

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Cyclooxygenase-2 in Cancer and Inflammatory Diseases

Cancer, which results from altered tissue growth regulation, is one of the leading causes of death worldwide.  Inflammation is the response of the immune system to infection and injury and has been implicated in the pathogeneses of arthritis and

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Matrix Binding microbes and bacteriophages to counter infection

Matrix binding proteins from probiotics and viruses:

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VALUE Virtual Simulation Labs

Virtual Lab: Amrita Vishwa Vidyapeetham is transforming the face of higher education and research, through a revolutionary new educational tool – virtual labs. The VALUE Initiative is a project dedicated to developing these virtual labs in

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Theoretical and Empirical Investigations on the Interaction of Asymmetric Migration and Intrinsic...

The dynamics of spatially structured populations (metapopulations) have been widely studied over the last few decades.

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Mass spectrometry based proteomic characterization of carbonylated proteins as indicators of...

Oxidative stress refers to the physiological stress caused by an imbalance between the systemic production of reactive oxygen species and the biological system's ability to detoxify the reactive intermediates.

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Identification and characterization of the role of Allium sativum-microbiome on the production of...

A wide range of plants have been harnessed for the development of remedies under the Ayurvedic system of medicine.

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Cost effective device and cloud enabled smart solution for diabetes care

The joint effort by Amrita and Wipro has the goal of making diabetes care available, accessible and affordable for the Indian masses. Amrita and Wipro has envisaged a patient-centric solution wherein low cost diabetes care devices (glucose strips

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Bio-inspired Processor Design for Cognitive Functions via Detailed Computational Modeling of...

This project aims at understanding cognitive functioning of cerebellar input layer and implement signal processing abilities into neural hardware using cerebellar architecture.

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Synthesis and characterization of lead salt based linear heterostructures for photovoltaic...

Quantum dots, also known as nanocrystals, are a special class of materials known as semiconductors, which are crystals composed of periodic groups of II-VI, III-V, or IV-VI materials. Their size ranges from 2-10 nanaometers.

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Process Development for Isolation and Characterization of Phytochemicals

In the Phytochemistry laboratory, development, analysis, and optimization of technical processes for target dependent bioactive compound isolations and assays are carried out. A brief account is given below.

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Computational Neuroscience and Cognitive Modeling

In contrast to other fields in biology, mathematical thinking and methodology have become entrenched in neuroscience since its very beginning, as witnessed by the classical work of Hodgkin and Huxley.

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Inventory of Vegetation with special reference to Medicinal and Aromatic Plants and Documentation...

A tropical forest, with its varied life forms, provides an array of resources and services, making life possible on earth. The major beneficial components include food, medicine, clothing and

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Role of miRNAs in cancer and modulation of oncogenes by natural products

Cancer known medically as a malignant neoplasm, is a broad group of diseases involving unregulated cell growth.

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Regulation of Inflammation by Natural Product extracts: Role in osteoclastogenesis

Inflammation is the body's endeavor at self-defense, the intent being to eradicate harmful stimuli, including damaged cells, irritants, or pathogens and begin the healing process.  It is one of the major steps in normal wound healing process with

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Synthesis of Modified Benzophenanthridine – a Preliminary Anti-Cancer Study

Benzophenanthridines, naturally occurring isoquinoline alkaloids with various biological activities, are known to exist in five plant families, namely, the Fumariaceae (Genera Corydalis, Dicentra and Fumaria), the Papaveraceae, and the Rutaceae

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Identification of Natural Product Lead molecules as Potential Modulators of Wound Healing and...

Wound healing is the result of a complex interplay between various cell types wherein macrophages and fibroblasts play a crucial role during various phases of the process.

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Marine Algae - An Important Source for Lectins

The role of various sugars on the surface glycans in bacterial /fungal pathogenesis of plants and animals is well known. The focus of our research group is to hit upon proteins which are capable of interacting with these sugars. A class of

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Studies On Antagonistic Effects Of Partially Purified Bacteriocins From Microflora Of Fermented...

Bacteriocins are antimicrobial peptides produced by bacteria that kill or inhibit the growth of other bacteria.

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Organic Bulk Heterojunction Devices for Photovoltaic Solar Cell Applications

This study proposes the investigation of “Bulk Heterojunction” solar cells consisting of different types of p-type (donor) and n-type (acceptor) network. The various chemicals proposed to be used in this study are metal phthalocyanines,

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MIMIC – A Unique approach to wound healing assays

Nowadays researchers are interested in cell patterning and here is a method used for patterning mammalian cells that does not require access to photolithographic capabilities. This work describes a versatile process for forming microstructures of

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Diversity Oriented Synthesis Applications to Flavonols, Flavones, Isoflavones and Biflavones

Divergent oriented synthesis is a strategy which aims to the synthesis of compounds with diverse chemical structures. It is often an alternative to convergent synthesis or linear synthesis.

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Development of Non-enzymatic Electrochemical Glucose Biosensors and Glucometer

Diabetes mellitus is a public health problem affecting millions of people worldwide. Commercially available glucose sensors are enzyme based and has numerous drawbacks including high cost and insufficient long-term stability, both of which

Read More


Amrita Insulin Pump and Low-cost, Automated Biomedical Devices

Diabetes is a chronic disorder characterized by abnormal blood glucose levels due to problems associated with insulin production and action. When glucose levels rise too high, diabetes becomes dangerous. Without medical care, it can increase the

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Development of a Lab-on-a-Chip (LoC) for detection of Glucose, Cholesterol and Kidney Function

The proposed work involves the fabrication of lab-on-a-chip (LOC) diagnostic device that incorporates non-enzymatic sensors for detection of glucose, cholesterol and creatinine. The device consists of a disposable microfluidic component that

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Isolation and Characterization of Primary Tumor Cells

 The lack of effective “in vitro” models to predict success of pharmacological therapy for patients with variety of cancer cell types demands the development of better experimental models to understand the pathophysiology of the disease and

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Synthesis of Intermediate Analogues for Biologically Active Molecules

Berberine, an isoquinoline alkaloid with a bright yellow color, is easily seen in most of the herb materials when found in significant amounts. Among Chinese herbs, the primary sources for

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Anacardic acid - a novel template for cancer therapy

Traditional Indian medicine has always captivated Indian researchers and medical practitioners for its application in various pathological conditions.

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Identification of Endophytes from Marine Algae by 16S rRNA sequencing

Endophytes/ endosymbionts from marine micro algae have recently gained attention as potential sources of bioactive secondary metabolites. Our aim is to isolate and identify the endophytes by molecular biology methods. 

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In vitro studies on pharmacological potential of mycoendophyte of Simarouba glauca

The exploration of endophytes is still an emerging field. Almost all plants seem to deliver endophytes with promising contents and activities. Simarouba glauca has a long history in herbal medicine as antiparasitic, antidysentric, antipyretic and

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Paraptosis: a Newer Approach to Target Cancer

The focus of the project is to screen molecules with anti-cancer properties and understand their mode of action with respect to cell death.

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Natural Dyes as Efficient Candidate for Enhancing the Photovoltaic Properties of Dye Sensitized...

The requirement of energy in India has been growing exponentially over the years. Since conventional energy options are futile to tackle this raise, the needs for non-conventional energy sources have become essential.

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Computational Chemistry & Molecular Docking Studies

Docking studies are computational techniques for the exploration of the possible binding modes of a substrate to a given receptor, enzyme or other binding site. The application of computational methods to study the formation of intermolecular

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Modulation of MicroRNA and Protein Signatures in Hepatocellular Carcinoma by Chemopreventive...

The current study will enable the elucidation of global miRNA expression profiles and identification of miRNA targets in response to intervention with chemopreventive phytochemicals in liver cancer.

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Mass Spectrometric Characterization of Bioactive Peptides and Proteins

Plant diseases caused by bacteria and fungi are the major reasons for significant loss in crop yields. To address this issue, many strategies have been developed and new bioanalytical tools have been utilized with an aim to control microbe

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Computational Modelling and Prediction of Cerebellar Input Layer function, Timing and Plasticity...

Investigating the organized activity of neuron ensembles is critical to understand how brain circuits work and is one main target of the project. Reconstruction of network activity has proved to be a hard task. This project will study cellular

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Low Cost Device and Cloud Enabled Smart Solution for Diabetes Care

In a unique partnership, Amrita Vishwa Vidyapeetham joined hands with Wipro Technologies, Bangalore to work on an end-to-end diabetes solution. The project entitled "Low Cost Device and Cloud Enabled Smart Solution for Diabetes Care" is funded by

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Benchtop Nanoscale patterning using soft lithography for the printing of DNA molecules

DNA microarrays have rapidly evolved to become one of the essential tools to examine expression or mutation of thousands of genes simultaneously.

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Neurophysiological Recording and Modeling Fast-response Timing of Granule and Golgi Cell Responses...

One main issue for cerebellum-based robotic models is to understand information processing in the cerebellar circuit in order to reproduce artificial networks able to perform analogous tasks in robotic control systems.

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Elucidating the Molecular Mechanisms of Anacardic Acid and Biacacetin Mediated Regulation of Matrix...

Cancer is the leading cause of death in economically developed countries and the second leading cause of death in developing countries like India.

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Chemically Modified Biopolymers : Synthesis, Characterization & Applications

The research activity in our laboratory aims at the development of novel biopolymer matrices with potential applications in waste water management, drug delivery etc. For instance, the β-oxothioamide derivative of chitosan biopolymer was found to

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Design and Validation of Point of Care Disposable Sensor Strips for Diagnosis of Tuberculosis from...

Tuberculosis (TB) is believed to affect nearly one third of the world population with approximately 9 million new cases detected every year. Current methods of diagnosis includes sputum smear microscopy, chest X-Ray and biopsy which are time

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Peptide-Based Anti-Snake Venom Therapy

Typically, a snake bite is treated with polyclonal antibody preparations obtained from immunized animals.

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Regulation of Inflammasomes by Natural Product extracts:Role in metabolic disorders

Inflammation is the body's endeavor at self-defense, the intent being to eradicate harmful stimuli, including damaged cells, irritants, or pathogens and begin the healing process.

Read More


Development of Heterotrophic and Phototrophic Microbial Fuel Cell

Apart from the various alternatives of conventional energy sources, electricity generated by microorganisms can be an important source of renewable energy. The Microbial Fuel Cell (MFC) which harnesses this potential, offers possibilities of

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Modulation of MicroRNA and Transcriptional Regulation of MMP-2 by Natural Products in Human Breast...

India is rich in plant biodiversity, and that has been utilized extensively in traditional medicine. In collaboration with Dr.

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Virtual Amrita Laboratories in Biotechnology

Amrita Virtual Biotechnology laboratory is a new kind of experimental science that is being established as a virtual simulation based laboratory.

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Studies On Antagonistic Effects Of Partially Purified Bacteriocins From Microflora Of Fermented Vegetables Against Enteric Pathogens

Bacteriocins are antimicrobial peptides produced by bacteria that kill or inhibit the growth of other bacteria. Bacteriocins differ from most therapeutic antibiotics in being proteinaceous and generally express a narrow specificity of action

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Label - Free Quantitative Proteomics Analysis to Study the Effect of Triclosan on Delta-Haemolysin: A Haemolytic Factor of Methicillin - Resistant Staphylococcus Aureus

Triclosan is a widely used biocide to prevent Methicillin-resistant Staphylococcus aureus (MRSA) outbreaks in hospitals. Lately, long term exposure to triclosan has resulted in certain strains showing susceptibility and thereby resistance and

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Electrospun TiO2 Nanofibers as a matrix to enhance the drug loading

The technique of Electrospinning has been considered as the most promising approach for the large scale production of nanofibers of varying diameter. It is quite a simple and efficient method for the nanofiber production.

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Apr
9
2016
Amrita Center for Computational Neurosciences and Neurophysiology at School of Biotechnology, Amritapuri campus has developed a computer model to understand the brain disorders. Besides neurological disorders, the approach based on accelerated computing platform can be extended to understand cancer, its origin and functional misbehavior and even infections spread through viruses.
Apr
9
2016
Amrita Center for Computational Neurosciences and Neurophysiology at School of Biotechnology, Amritapuri campus has developed a computer model to understand the brain disorders. Besides neurological disorders, the approach based on accelerated computing platform can be extended to understand cancer, its origin and functional misbehavior and even infections spread through viruses.
Apr
9
2016
Amrita Center for Computational Neurosciences and Neurophysiology at School of Biotechnology, Amritapuri campus has developed a computer model to understand the brain disorders. Besides neurological disorders, the approach based on accelerated computing platform can be extended to understand cancer, its origin and functional misbehavior and even infections spread through viruses.
Apr
9
2016
Amrita Center for Computational Neurosciences and Neurophysiology at School of Biotechnology, Amritapuri campus has developed a computer model to understand the brain disorders. Besides neurological disorders, the approach based on accelerated computing platform can be extended to understand cancer, its origin and functional misbehavior and even infections spread through viruses.
Apr
9
2016
Center for Computational Neurosciences and Neurophysiology at School of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri has developed a computer model to understand the brain disorders. Besides neurological disorders, the approach based on accelerated computing platform can be extended to understand cancer, its origin and functional misbehavior and even infections spread through viruses.
Apr
1
2016
Amrita Vishwa Vidyapeetham’s Computational Neuroscience Lab, part of the School of Biotechnology, has been using the NVIDIA Tesla Accelerated Computing Platform to design prediction models for neurological disorders and to better understand neural circuit function. This work will ultimately help pioneer treatments for brain disorders and dysfunctions, as well as support developments in engineering and robotics. Shyam Diwakar, is the Lab Director of Computational Neuroscience and Neurophysiology Labs. 
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