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The Systems Genomics lab coalesces interests in the areas of bioinformatics aided functional genomics, third generation sequencing technologies with a focal interest on identifying candidate non-coding mutations for causality. The group has developed annotation based methods in inferring the causal SNPs from sequence data for determining bona fidelity. The lab interests in exploring the known unknown regions in the human genome, elucidating the mechanisms underpinning small molecular interactions through clinical exomes. The group has benchmarked pipelines and developed methods for systems genomic integration in lieu of the following:

  • Characterizing the uncharacterised regions in the genome: Develop methods for identifying regulatory regions, elements associated with diseased genes and proteins
  • Next Generation Sequencing (NGS) of rare disease genomics and CA Prostate
  • Systems Genomics of Vitamin K Pathways
  • LncRNA-protein interactions in ascertaining diseasome networks


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System Genomics and Bioinformatics
School of Biotechnology
Amrita Vishwa Vidyapeetham, Amritapuri Campus, Clappana P.O.
Kollam – 690525, Kerala, India


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