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Course Detail

Course Name Cell Biology
Course Code BIO 421
Program M. Sc. in Bioinformatics
Semester One
Credits Three
Year Taught 2019


Tools of cell biology. Ultra structure of prokaryotic and eukaryotic cells, organelles structure marker and function, Endoplasmic reticulum, Golgi complex, Types of vesicles – transport and their functions, Lysosomes. Nucleus – Internal organization, Nuclear pore complex, Nucleosomes Chromatin. Mitochondrial Genome, Structure and Function – Oxidative Metabolism in the Mitochondrion – The Role of Mitochondria in the formation of ATP – Translocation of Protons and the Establishment of a proton-motive force – The Machinery for ATP formation – Peroxisomes. Genome studies of Mitochondria. Chloroplast structure and function – An overview of photosynthetic Metabolism, Cytoskeleton – components of Cytoskeleton, Microtubules, Intermediate filaments – Microfilaments, Protein trafficking, Cell- to -Cell Signaling: Hormones and Receptors, Intracellular signaling in Development and Disease, Transport across Cell Membranes, Protein Sorting: Organelle Biogenesis and Protein secretion, Stem Cell Biology, Cancer, Regulation of Cell Death; Apoptosis, Circadian Rhythms.

Text Books

  1. “Molecular Cell Biology”  5th Edition by Harvey Lodish, Arnold Berk, Paul Matsudaira, Chris Kaiser, Monty Krieger, Matthew Scott, Lawrence Zipursky and James Darnell.  W.H Freeman and Company.
  2. The Cell A Molecular Approach-Cooper-Hausman


  1. Molecular Biology of the Cell- Bruce Alberts et al.

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