Tools of cell biology. Ultra structure of prokaryotic and eukaryotic cells, organelles structure marker and function, Endoplasmic reticulum, Golgi complex, Types of vesicles – transport and their functions, Lysosomes. Nucleus – Internal organization, Nuclear pore complex, Nucleosomes Chromatin. Mitochondrial Genome, Structure and Function – Oxidative Metabolism in the Mitochondrion – The Role of Mitochondria in the formation of ATP – Translocation of Protons and the Establishment of a proton-motive force – The Machinery for ATP formation – Peroxisomes. Genome studies of Mitochondria. Chloroplast structure and function – An overview of photosynthetic Metabolism, Cytoskeleton – components of Cytoskeleton, Microtubules, Intermediate filaments – Microfilaments, Protein trafficking, Cell- to -Cell Signaling: Hormones and Receptors, Intracellular signaling in Development and Disease, Transport across Cell Membranes, Protein Sorting: Organelle Biogenesis and Protein secretion, Stem Cell Biology, Cancer, Regulation of Cell Death; Apoptosis, Circadian Rhythms.