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Pancreatitis in the setting of the metabolic syndrome

Publication Type : Journal Article

Publisher : Indian Journal of Gastroenterology

Source : Indian Journal of Gastroenterology, Volume 31, Number 2, p.79-82 (2012)

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Keywords : acanthosis nigricans, acute hemorrhagic pancreatitis, acute pancreatitis, adolescent, adult, age distribution, alanine aminotransferase, alanine aminotransferase blood level, amylase, amylase blood level, article, aspartate aminotransferase, aspartate aminotransferase blood level, body mass, child, cholesterol blood level, clinical article, conservative treatment, controlled study, diabetes mellitus, disease association, disease severity, gliclazide, Glucose, glucose blood level, high density lipoprotein cholesterol, human, Humans, hyperglycemia, hypertriglyceridemia, insulin, Intra-Abdominal Fat, laboratory test, Liver disease, male, medical record, metabolic syndrome X, metformin, pancreas enzyme, pancreas pseudocyst, pancreatitis, Recurrence, recurrent disease, relative, school child, triacylglycerol, triacylglycerol blood level, weight reduction, Young Adult

Campus : Kochi

School : School of Medicine

Department : Endocrinology, Gastroenterology

Year : 2012

Abstract : There is paucity of literature on the relation of obesity with recurrent and chronic pancreatitis. We recorded the clinical details and the outcome of five patients with recurrent pancreatitis who had components of the metabolic syndrome. Their age ranged from 8 to 20 years. All five patients had acanthosis nigricans. Body mass index (BMI) could not be evaluated as these patients lost weight following episodes of pancreatitis. Three patients had two or more first-degree relatives who had diabetes mellitus. Only one patient had severe necrotizing pancreatitis. Coexisting liver disease was seen in two patients. Elevated serum cholesterol levels and moderately elevated serum triglycerides along with elevated serum amylase levels observed in these patients suggest possibility of a different mechanism from that of hypertriglyceridemia-related pancreatitis. Evaluation of pancreatic steatosis should be considered in patients with pancreatitis in the setting of metabolic syndrome. © 2012 Indian Society of Gastroenterology.

Cite this Research Publication : Ga Rajesh, Kumar, Hb, Menon, Sa, and Balakrishnan, Va, “Pancreatitis in the setting of the metabolic syndrome”, Indian Journal of Gastroenterology, vol. 31, pp. 79-82, 2012.

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