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Publication Type : Journal Article
Thematic Areas : Nanosciences and Molecular Medicine
Publisher : Journal of Bionanoscience .
Source : Journal of Bionanoscience (2016)
Campus : Kochi
School : Center for Nanosciences
Center : Nanosciences
Department : Nanosciences
Year : 2016
Abstract : Ayurvedic medicines are kind of medications which are having less side effects and more efficacy, but lack scientific explanations about their mechanism that hindered its world wide acceptance. With the emergence of nanotechnology, the concept of nanomedicines in cancer therapy attracts tremendous attention due to its novel drug formulation routes, site-specific action, better solubility, improved efficacy and reduced side effects, even though the 5000-year-old Indian system of ayurvedic medicines have been using the concept long before. Tinospora cordifolia is a medicinal plant used alone or in combination with other herbal drugs for different cancer therapy. In this present study, we explored the role of nanoformulation of Tinospora cordifolia stem extract in prostate cancer cells. From our experiments, it was observed that there is no significant apoptosis induction, but stops proliferation in cancer cells and are compatible with erythrocytes and normal cells. Hence, we can conclude that the drug is an anti proliferative agent for prostate cancer treatment.
Cite this Research Publication : K. S., K.S., S., K.C., R., Shantikumar V Nair, and K., L. V., “Anti-Proliferative Effect of Tinospora cordifolia Nano Particles in Prostate Cancer Cells”, Journal of Bionanoscience, 2016.