Unit 1

Introduction: History and need for biochemical Engineering; Essential life sciences: Biomolecules; Microbial world; Metabolism and Bioenergitics; Cell and their function; Enzymes and enzyme kinetics: Enzymes fundamental concepts, Classification of enzymes; Industrial application of enzymes; Industrially important enzymes; Mechanism of enzymatic reactions; Kinetics: Michaelis-Menten and Briggs Haldane equation; Evaluation of kinetic parameters; Enzymes inhibition; Factors affecting the reaction rates;

Unit 2

Immobilized enzyme: Medical and analytical application of immobilized enzyme; Techniques; Immobilized Enzyme kinetics: Effect of mass transfer resistance. Microbial kinetics: Typical growth characteristics of microbial cells, factors affecting growth; Monod’s equation; Transport in microbial system: Newtonian and NonNewtonian behaviour of broths; Agitation and Mixing; Power consumption; Gas– Liquid transport in cells; Transfer resistances; Mass transfer coefficients and their role in scale–up of equipments.

Unit 3

• J. M. Lee, “Biochemical Engineering”, 1^st Edition, Prentice Hall, 1992
• H. W. Blanch and D. S. Clark, “Biochemical Engineering”, 2^nd Edition, CRC Press, 1997.
• M. L.Shuler and F. Kargi, “Bioprocess Engineering Basic Concepts”, Prentice Hall of India, 2002.
• D. Mukesh and N. G. Sathyanarayana, “Biochemical Engineering”, PHI Learning Pvt. Ltd., 2007