Back close

Course Detail

Course Name Bioenergetics & Metabolism
Course Code BIO 311
Program BSc. in Biotechnology
Semester Five
Credits Three
Year Taught 2019



Chapter 1: Bioenergetics:. Thermodynamics –First law of thermodynamics, second law of thermodynamics, Gibbs free energy, endergonic & exergonic reactions,. Standard state free energy changes-DG, DG0 and DG’0, Relationship between equilibrium constant and DG’o, Feasibility of reactions. Simple problems, ATP-Structure, properties and energy currency of the cell, Importance of Coupled reactions, High energy compounds, simple problems. Introduction to Metabolism – Catabolism, anabolism, catabolic, anabolic and amphibolic pathways


Chapter 2: Carbohydrate Metabolism: Introduction, Aerobic and anaerobic pathways: Glycolysis and its regulation ,  Gluconeogenesis and its regulation.TCA cycle, amphibolic & anaplerotic reactions. Electron Transport chain, Oxidative phosphorylation, & production of ATP, balance sheet of glucose oxidation, Oxidative stress.,  Pentose phosphate pathway (HMP shunt) & its regulationPhotosynthesis – ‘light’ and ‘dark’ reactions: C4-pathway.


Chapter 3: Lipid Metabolism: Beta – oxidations of saturated & unsaturated fatty acids. Ketone bodies, production during starving and diabetes Biosynthesis of fatty acids – Acetyl-CoA carboxylase reaction, Fatty acid synthase complex, biosynthesis of palmitate, energetics, Regulation of fatty acid biosynthesis. Biosynthesis of triacylglycerols, Biosynthesis of cholesterol, regulation.


Chapter 4: Amino Acid/ Nucleic Acid Metabolism: Biodegradation of amino acids – deamination, transamination, decarboxylation, urea cycle including its regulation. Biosynthesis of amino acids, Disorders of amino acid metabolism (phenylketonuria, alkaptonuria, Biologically active amines Recycling of Purine and Pyrimidine nucleotides by salvage pathways. Lesch-Nyhan syndrome & Gout.

Syllabus - Year Taught
2015 2014

Text Books

  1. Lehninger, Nelson and Cox, Principles of Biochemistry, 4th Edition, W.H.Freeman & Company, 2004.
  2. Voet & Voet, Fundamentals of Biochemistry, Upgrade Edition, Wiley, 2002.
  3. Lubert Stryer, Biochemistry, 4th Edition, W.H.Freeman and Company, 1995


DISCLAIMER: The appearance of external links on this web site does not constitute endorsement by the School of Biotechnology/Amrita Vishwa Vidyapeetham or the information, products or services contained therein. For other than authorized activities, the Amrita Vishwa Vidyapeetham does not exercise any editorial control over the information you may find at these locations. These links are provided consistent with the stated purpose of this web site.

Admissions Apply Now