Quantum mechanics – Schrodinger’s time dependent and independent equations – Pauli’s exclusion principle – ionization energy – electron affinity – chemical binding – electro negativity and strong bonds - secondary bonds – inter atomic potential for strong bonds and weak bonds – bond energies – spring constants – free energy – internal energy – reaction kinetics.
Definition and classification of bio-materials, mechanical properties, visco-elasticity, wound-healing process, Application of biomaterial for the human body, body response to implants, blood compatibility. Implementation problems - inflammation, rejection, corrosion, structural failure. Surface modifications for improved compatibility.
Bioceramics, Biopolymers, Metals, ceramics and composites in medicine: Properties, applications, suitability & modifications required for certain applications.
X-ray diffraction and molecular structure – Nuclear Magnetic Resonance – scanning tunneling microscope – Atomic force microscopy – optical tweezers – patch clamping – molecular dynamics – potential energy contour tracing – SEM – TEM – spectroscopy methods differential thermal analysis, differential thermo gravimetric analysis – NDT methods.
Materials for bone and joint replacement – dental metals and alloys – ceramic – bioinert – bioactive ceramics – polymers - dental restorative materials – dental amalgams – cardiovascular materials – cardiac prosthesis; vascular graft materials – cardiac pacemakers – cardiac assist devices – materials for ophthalmology contact lens – intraoccular materials – materials for drug delivery