## Course Detail

 Course Name Biostatistics Course Code 24AIM311 Program B.Tech. in Artificial Intelligence (AI) and Data Science (Medical Engineering) Semester VI Credits 3 Campus Coimbatore

### Syllabus

##### Unit 1

Need of biostatistics Descriptive statistics: Population and samples descriptive methods for categorical data descriptive methods for continuous data probability and probability distributions types of data frequency distribution measures of central tendency measures of variability kurtosis and skewness Z score

##### Unit 2

Inferential statistics Parameters estimating and comparing the mean of population. Hypothesis testing: basic concepts and steps testing normal distribution – Kolmogorov-Simon test testing homogeneity of variance – Levine’s test Z-tests dependent t-test, independent t-test, t-test as GLM, F-test, Chi-square test Type I and type II errors ANOVA, ANCOVA, factorial ANOVA, repeated-measures designs, mixed design ANOVA, post hoc procedures.

##### Unit 3

Non-parametric tests non-parametric and distribution-free tests – Mann-Whitney test Wilcoxon signed-rank test, Wilcoxon signed rank sum test, Kruskal-Wallis test, Friedman’s ANOVA.

##### Unit 4

Correlation techniques Bivariate correlation – Pearson’s correlation coefficient, Spearman’s correlation coefficient Partial correlation regression – method of least squares, assessing goodness of fit multiple regression. Experimental design and clinical trials.

### Course Objectives and Outcomes

Course Objectives:

To impart training on basic biostatistics and use of various statistical tools for biomedical data analysis.
To apply statistical tools in experimental design and clinical trials

Course Outcomes:

After completing this course, students should be able to
CO1: Effectively analyze and summarize both categorical and continuous data using descriptive statistics.
CO2: Apply inferential statistics, including hypothesis testing and parametric tests, for meaningful interpretations and decisions.
CO3: Demonstrate proficiency in non-parametric tests and correlation techniques for data analysis.
CO4: Utilize statistical analysis and understand its applications in experimental design and clinical trials.

CO-PO Mapping

 PO/P SO PO 1 PO2 PO3 PO4 PO5 PO 6 PO7 PO8 PO 9 PO 10 PO 11 PO 12 PSO 1 PSO2 PSO3 CO CO1 1 – – – – – – – 2 2 – 2 3 2 2 CO2 – 2 – 3 – – – – 2 2 – 2 3 2 2 CO3 – 3 1 — 3 – – – 2 2 – 2 3 2 CO4 – – – – 1 1 2 2 2 2 – 2 3 2 2

### References

1. Eberly, L. E., Le, C. T., Introductory Biostatistics. Germany: Wiley, 2016.
2. Glaser, A. N. High-yield Biostatistics. United States: Lippincott Williams & Wilkins, 2001.
3. Advances in Clinical Trial Biostatistics, United States: Taylor & Francis. 2003.

DISCLAIMER: The appearance of external links on this web site does not constitute endorsement by the School of Biotechnology/Amrita Vishwa Vidyapeetham or the information, products or services contained therein. For other than authorized activities, the Amrita Vishwa Vidyapeetham does not exercise any editorial control over the information you may find at these locations. These links are provided consistent with the stated purpose of this web site.