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Course Detail

Course Name Cell and Molecular Biology
Course Code 24TM502
Program M.Sc. in Translational Medicine
Semester I
Credits 3
Campus Faridabad


Unit 1:
Introduction to Cell Biology; Cell structure and organelles, Membrane dynamics and trafficking, Cytoskeleton and cell motility.
Unit 2:
Molecular Biology of Gene Expression, Transcriptional regulation, RNA processing and translation, Epigenetics and chromatin remodeling.
Unit 3:
Cell Signaling and Communication, Receptor-mediated signaling pathways, Intracellular signaling cascades, Cell-cell communication and intercellular signaling.
Unit 4:
Cell Cycle Regulation and Cell Division; Cell cycle checkpoints and regulation, Mitosis and cytokinesis, Cell cycle control and cancer.
Unit 5:
Stem Cells and Developmental Biology; Stem cell niches and pluripotency, Differentiation and lineage commitment, Regeneration and tissue repair.
Unit 6:
Cancer Biology and Oncogenes; Hallmarks of cancer, Oncogenes and tumor suppressor genes, Cancer stem cells and therapeutic implications.
Unit 7:
Techniques in Cell and Molecular Biology; Immunofluorescence and microscopy, Western blotting and protein analysis, PCR, qPCR, and gene expression analysis.
Unit 8:
Emerging Topics in Cell and Molecular Biology; Single-cell analysis techniques, CRISPR/Cas9 genome editing, Organelle dynamics and cell imaging.

Objectives and Outcomes

Course outcome

CO1: To gain a comprehensive understanding of cell structure, function, and organization.

CO2: To explore molecular mechanisms governing cellular processes such as gene expression, signal transduction, and cell cycle regulation.

CO3: To examine recent advances in areas such as stem cell biology, developmental biology, and cancer biology.

CO4: To develop critical thinking and analytical skills through the evaluation of primary research literature.

CO5: To gain hands-on experience with laboratory techniques commonly used in cell and molecular biology research.

Program outcome (PO)

PO1: Utilize scientific principles and methodologies to design innovative solutions for data analysis, experimentation, and product development for challenges in translational research.

PO2: Recognize the importance of environmental sustainability in translational research and strive to minimize adverse environmental impacts.

PO3: Engage in ethical conduct, leadership, active listening, constructive feedback, and interpersonal communication to facilitate productive collaborations and knowledge exchange.

PO4: Acquire fundamental and advanced knowledge and skills in project management, financial planning, and entrepreneurship relevant to translational research ventures and initiatives.

3 = High Affinity, 2 = Medium Affinity, 1 = Low Affinity, – = No Affinity

CO 1 2 1 3
CO 2 2 1 3
CO 3 3 2 1 3
CO 4 3 1 3
CO 5 2 2 3

Program Specific Outcome (PSO)

PSO1: Addresses the complexity of interdisciplinary sciences in biological and medical contexts.

PSO2: Deals with regulatory affairs in medicine, covering topics such as ethical considerations and regulatory frameworks.

PSO3: Covers compounds as drugs and their efficacy, involving pharmacology and drug development.

PSO4: Explores the intersection of bioinformatics and artificial intelligence in biology and medicine.

PSO5: Deals with technology in personalizing medicine, involving precision medicine approaches.

PSO6: Focuses on communicating and disseminating science and medicine to the public, involving science communication and public outreach efforts.

CO 1 3 3 2
CO 2 3 3 3 2
CO 3 3 1 3 2
CO 4 3 2 3 2 2
CO 5 3 1 3 3 2


Alberts, B., 2017. Molecular biology of the cell. (5th Edition) Garland science.
Lodish, H.F., 2008. Molecular cell biology. (7th Edition) Macmillan.

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