Unit 1
Introduction to Toxicology: Definition – scope – history – relationship to other sciences – dose-response relationship – sources of toxic compounds – Classes of Toxicants – broad overview of toxicant classes such as metals, agricultural chemicals, food additives – contaminants, toxins, solvents, drugs, and cosmetics – history, exposure route, and toxicity of the non-essential metals – cadmium, lead, and mercury – medical treatment of metal poisoning – classes of agricultural chemicals – Toxins – source, including microbial, fungal, algal, plant and animal – examples – Brief discussions – food additives and contaminants – solvents – therapeutic drugs – drugs of abuse – combustion products – cosmetics.