Unit 1
Morphology of bacteria: Shape of bacteria, bacterial cell wall, cell membrane, cytoplasmic matrix, cell wall appendages, bacterial spores
| Course Name | Clinical Microbiology |
| Course Code | 24MMD533 |
| Program | M. Sc. Molecular Medicine(MLM) |
| Semester | 1 |
| Credits | 3 |
| Campus | Faridabad, Kochi |
Morphology of bacteria: Shape of bacteria, bacterial cell wall, cell membrane, cytoplasmic matrix, cell wall appendages, bacterial spores
Physiology of bacteria: Bacterial growth and nutrition, factors affecting growth of bacteria, bacterial metabolism
Laboratory diagnosis of bacterial infections: Specimen collection, staining techniques, culture, identification and AST, culture methods, aerobic and anaerobic methods of culture, identification of microbes, antimicrobial susceptibility testing, serology, molecular methods.
Antimicrobial agents and antimicrobial resistance: Antimicrobial agents, antimicrobial resistance, mechanism of antimicrobial resistance.
Pathogenesis of bacterial infections: Mechanism of bacterial pathogenesis, route of transmission, infective dose, intracellular survival, toxins, overview of bacterial infections.
General Virology: Morphology of viruses, viral replication, pathogenesis of viral infections, isolation and cultivation of viruses, treatment of viral diseases, viral vaccines
Overview of viral infections: Herpers viruses, other DNA viruses, Myxoviruses, Rubella, Corona, Picornaviruses, Arboviruses, Rabies, HIV, Hepatits.
Pre-requisites: Basic understanding of microbiology
Total number of classes: 45
Preamble
The candidates undertaking this course will gain knowledge about fundamentals of microbiology with special reference to bacterial, viral and fungal diseases; and host responses against infections. The scientific understanding developed through the course will motivate the student to take up advanced microbiology courses that has extensive application in medicine.
Course Outcome
CO1 Students will develop a comprehensive understanding of the morphology, physiology, and growth dynamics of bacteria, viruses, and fungi, including their cellular structures, growth requirements, and metabolic pathways.
CO2 Students will acquire proficient laboratory skills in diagnosing microbial infections, including specimen collection techniques, staining procedures, culture methods, and antimicrobial susceptibility testing, utilizing both conventional and molecular techniques.
CO3 Students will learn to critically evaluate antimicrobial agents, understand mechanisms of antimicrobial resistance, and apply strategies for the effective management and control of antimicrobial resistance in clinical settings.
CO4: Students will gain an in-depth understanding of microbial pathogenesis, transmission routes, infective doses, and virulence factors contributing to bacterial, viral, and fungal infections, and will be equipped with infection control measures to mitigate their spread in healthcare settings.
CO5: Students will demonstrate competence in selecting and implementing appropriate sterilization and disinfection protocols, including knowledge of sterilants, disinfectants, cleaning agents, and biological indicators, to ensure the prevention of healthcare-associated infections and maintain aseptic environments.
PO1: Bioscience Knowledge
PO2: Problem Analysis
PO3: Design/Development of Solutions
PO4: Conduct Investigations of complex problems
PO5: Modern tools usage
PO6: Bioscientist and Society
PO7: Environment and Sustainability
PO8: Ethics
PO9: Individual & Team work
PO10: Communication
PO11: Project management & Finance
PO12: Lifelong learning
|
c |
PO1 |
PO2 |
PO3 |
PO4 |
PO5 |
PO6 |
PO7 |
PO8 |
PO9 |
PO10 |
PO11 |
PO12 |
|
C O |
||||||||||||
|
CO 1 |
3 |
1 |
1 |
1 |
– |
– |
– |
– |
– |
– |
– |
1 |
|
CO 2 |
3 |
1 |
1 |
– |
– |
– |
– |
– |
– |
– |
– |
1 |
|
CO 3 |
3 |
1 |
1 |
– |
– |
– |
1 |
|||||
|
CO 4 |
3 |
1 |
1 |
1 |
– |
– |
– |
– |
– |
– |
– |
1 |
|
CO 5 |
3 |
1 |
1 |
1 |
1 |
– |
– |
– |
– |
– |
– |
1 |
Program Specific Outcomes. (PSO)
PSO 1 – Biochemical organization and cellular complexity in function
PSO 2 – Biomolecules in Medicine
PSO 3 – Molecular basis of disease
PSO 4 – Molecular technology in diagnosis and therapy
PSO 5 – Cellular based approaches in diagnosis and therapy
PSO 6 – Microorganisms in Medicine
PSO 7 – Nanoscale entities and its significance in Medicine
PSO 8 – Tissue architecture engineering in Medicine
PSO 9 – Compounds as drugs and its efficacy
PSO 10 – Bioinformatics and biological data use
|
– |
PSO1 |
PSO2 |
PSO3 |
PSO4 |
PSO5 |
PSO6 |
PSO7 |
PSO8 |
PSO9 |
PSO10 |
|
C O |
||||||||||
|
CO 1 |
3 |
1 |
2 |
– |
– |
3 |
– |
– |
1 |
– |
|
CO 2 |
3 |
– |
1 |
– |
– |
– |
– |
– |
– |
– |
|
CO 3 |
3 |
1 |
1 |
– |
1 |
– |
– |
– |
– |
– |
|
CO 4 |
3 |
– |
1 |
– |
– |
– |
– |
– |
– |
– |
|
CO 5 |
3 |
– |
3 |
– |
2 |
– |
– |
– |
– |
– |
Evaluation Pattern: 50+50 = 100
|
Internal Assessment – 50% |
||
|
Periodical 1 |
Exam |
20% |
|
Periodical 2 |
Exam |
20% |
|
Continuous Assessment |
Assignment/Test/Quiz |
10% |
|
50% |
||
|
End Semester Examination- 50% |
||
|
Theory Exam |
50% |
|
|
50% |
||
|
Total |
100% |
|
Text Book
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