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Course Detail

Course Name Intelligence of Biological Systems 2
Course Code 19BIO112
Program B. Tech. in Computer Science and Engineering (Artificial Intelligence)
Semester 2
Year Taught 2019


DNA replication – genome – hidden messages in the genome – Python Programming and packages for Bioinformatics – Finding Replication Origins – DnaA boxes – Counting words – The Frequent Words Problem – Frequent words in Vibrio cholera – encodings in DNA to maintain circadian rhythm – Hunting for Regulatory Motifs – Motif Finding – Scoring Motifs – Greedy Motif Search – Randomized Motif Search – Gibbs Sampling.

Objectives and Outcomes

Course Objectives

The course will aim at introducing the concepts pertaining to DNA replication and will equip the students to explore the question where in the genome does the DNA replication will begin. Further it will motivate the students to investigate the origin of various rhythms observed in human body such as circadian rhythm and how they are encoded in the DNA

Course Outcomes

CO1 To investigate DNA replication.
CO2 To investigate the encodings in DNA to maintain various rhythms associated with the body.
CO3 To introduce state of the art computational algorithms to understand DNA encodings.


PO1 PO2 PO3 PO4 PO5 PO6 PO7 PO8 PO9 PO10 PO11 PO12
CO1 2 3 2 2 3 2 2 3 2 3 3
CO2 1 3 3 2 3 2 2 3 2 3 3
CO3 1 2 3 3 3 2 2 3 2 3 3


Course Evaluation Pattern:

Internal – 75%

  • Assignments – 50% (20 assignments with equal credit)
  • Quiz- 25% (5 Quizzes with equal credit)

External – 25%

  • Project – 25%

Text Books / References

  1. Philip Compeau and PavelPevzener, Finding Hidden Messages in DNA, Active Learning Publishers 2015.

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