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Course Detail

Course Name Medicinal Chemistry – Theory
Program Pharm. D.
Semester Five & Six
Year Taught 2014 , 2015 , 2016 , 2017 , 2018


‘Medicinal Chemistry – Theory’ is a course offered in the third year of Pharm. D. program at School of Pharmacy, Health Sciences campus, Amrita Vishwa Vidyapeetham.

Scope & Objectives

Course Duration: 3 Hrs./Week


Modern concept of rational drug design: A brief introduction to Quantitative Structure Activity Relationaship (QSAR), prodrug, combinatorial chemistry and computer aided drug design (CADD) and concept of antisense molecules.
A study of the development of the following classes of drugs including SAR, mechanism of action, syn- thesis of important compounds, chemical nomenclature, brand names of important marketed prod- ucts and their side effects.

  1. Anti-infective agents
    1. Local anti-infective agents
    2. Preservatives
    3. Antifungal agents
    4. Urinary tract anti-infectives
    5. Antitubercular agents
    6. Antiviral agents and Anti AIDS agents
    7. Antiprotozoal agents
    8. Anthelmentics
    9. Antiscabies and Antipedicular agents
  2. Sulphonamides and sulphones
  3. Antimalarials
  4. Antibiotics
  5. Antineoplastic agents
  6. Cardiovascular agents
    1. Antihypertensive agents
    2. Antiscabies and Antipedicular agents
    3. Antianginal agents and vasodilators
    4. Antiarrhythmic agents
    5. Antihyperlipidemic agents
    6. Coagulants and Anticoagulants
    7. Endocrine
  7. Hypoglycemic agents
  8. Thyroid and Antithyroid agents
  9. Diureties
  10. Diagnostic agents
  11. Steroidal Hormones and Adrenocorticoids

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