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Course Detail

Course Name Molecular biology and basic cellular physiology
Course Code 24AIM112
Program B.Tech. in Artificial Intelligence (AI) and Data Science (Medical Engineering)
Semester II
Credits 3
Campus Coimbatore


Unit 1:

Cells and their long-term structure-control mechanisms (basic molecular biology: genes, exons, introns, histones, chromatin accessibility, transcription factors, etc.)

Unit 2

Overall metabolic crossovers (Biological gates and switches, Transcription Regulation, Feed-forward and Feedback loops, Biological Networks, Introduction to Systems biology)

Unit 3

Cellular/systemic short-term powering & homeostasis & coherence, murburn concept (including xenobiotics and their modes of interaction), Cell-cell, cell-matrix, cell-environment interactions, etc.

Course Objectives and Outcomes

Course Objectives:

  • Develop a fundamental understanding of basic molecular biology concepts, including genes, exons, introns, histones, chromatin accessibility, and transcription factors.
  • Explore overall metabolic crossovers, including biological gates and switches, transcription regulation, feed-forward and feedback loops
  • Understand cellular and systemic powering, homeostasis, coherence, and murburn concept.

Course Outcomes:

After completing this course, students should be able to
CO1: Analyze and interpret fundamental molecular biology concepts, including the structure and control mechanisms of cells.
CO2: Demonstrate and apply concepts related to metabolic crossovers, biological gates, switches, transcription regulation, and the principles of systems biology.
CO3: Develop an understanding of cellular and systemic powering, homeostasis, coherence, and the murburn concept, including the interactions of cells with xenobiotics and their roles in cell-cell, cell-matrix, and cell-environment interactions.

CO-PO Mapping

CO1 3 2 2 2 2 3 3 3
CO2 2 2 2 2 3 3 3
CO3 2 2 2 2 3 3 3

Textbook / References:

  1. Nelson, D.L. and Cox, M.M. (2017) Lehninger Principles of Biochemistry. 7th Edition, W.H. Freeman, New York, 1328.
  2. Basic concepts in biochemistry: A student’s survival guide by Hiram F Gilbert. pp 298. McGraw-Hill, NY. 1992.
  3. Bruce Alberts … [and others]. Molecular Biology of the Cell. New York :Garland Pub., 1989.
  4. Pelczar, M.J., Chan, E.C.S. and Kreig, N.R. (2002) Microbiology. 5th Edition, Tata McGraw-Hill, New Delhi.
  5. Mescher A.L.(Ed.), [publicationyear2] Junqueira’s Basic Histology: Text and Atlas, 15e. McGraw-Hill Education.
  6. Richard L. Drake, A. Wayne Vogl, Adam W. M. Mitchell. Gray’s anatomy for students. Elsevier. ISBN : 9780323934237
  7. Gloria Doran, Cell physiology. Callisto Reference. ISBN-10:163239815X
  8. Stuart Ira Fox Dr and Krista Rompolski Human physiology by Fox & Rompolsk
  9. Dunecan Massey & Imran Noorani. Carpenter’s Neurophysiology: A Conceptual Approach.  ISBN-10 ‏ : ‎ 0367340607
    Neurophysiology by Carpenter
  10. Murburn concept in cellular function and bioenergetics: Part 1: Understanding murzymes at the molecular level. Manoj etal.
  11. Murburn concept in cellular function and bioenergetics: Part 1: Understanding integrations-translations from molecular to macroscopic levels. Manoj etal.

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