COURSE SUMMARY
Course Title: 
Pharmaceutics I - Theory
Course Code: 
BP103T
Year Taught: 
2014
2015
2016
2017
2018
Semester: 
1
Degree: 
Undergraduate (UG)
School: 
School of Pharmacy
Campus: 
Kochi

'Pharmaceutics I - Theory' is a course offered in the first semester of B. Pharm program at School of Pharmacy, Health Sciences campus, Amrita Vishwa Vidyapeetham.

Scope:

This course is designed to impart a fundamental knowledge on the preparatory pharmacy with arts and science of preparing the different conventional dosage forms.

Objectives:

Upon completion of this course the student should be able to:

  1. Know the history of profession of pharmacy
  2. Understand the basics of different dosage forms, pharmaceutical incompatibilities and pharmaceuti- cal calculations
  3. Understand the professional way of handling the prescription
  4. Preparation of various conventional dosage forms

Unit 1

Historical background and development of profession of pharmacy: History of profession of Phar- macy in India in relation to pharmacy education, industry and organization, Pharmacy as a career, Pharmacopoeias: Introduction to IP, BP, USP and Extra Pharmacopoeia.

Dosage forms: Introduction to dosage forms, classification and definitions

Prescription: Definition, Parts of prescription, handling of Prescription and Errors in prescription.

Posology: Definition, Factors affecting posology. Pediatric dose calculations based on age, body weight and body surface area.

Unit II

Pharmaceutical calculations: Weights and measures – Imperial & Metric system, Calculations involving percentage solutions, alligation, proof spirit and isotonic solutions based on freezing point and molecular weight.

Powders: Definition, classification, advantages and disadvantages,Simple & compound powders – official preparations, dusting powders, effervescent, efflorescent and hygroscopic powders, eutectic mixtures. Geometric dilutions.

Liquid dosage forms: Advantages and disadvantages of liquid dosage forms. Excipients used in for- mulation of liquid dosage forms. Solubility enhancement techniques

Unit III

Monophasic liquids: Definitions and preparations of Gargles, Mouthwashes, Throat Paint, Eardrops, Nasal drops, Enemas, Syrups, Elixirs, Liniments and Lotions.

Biphasic liquids:

Suspensions: Definition, advantages and disadvantages, classifications, Preparation of suspensions; Flocculated and Deflocculated suspension & stability problems and methods to overcome.

Emulsions: Definition, classification, emulsifying agent, test for the identification of type ofEmulsion, Methods of preparation & stability problems and methods to overcome.

Unit IV

Suppositories: Definition, types, advantages and disadvantages, types of bases, methods of prepara- tions. Displacement value & its calculations, evaluation of suppositories.

Pharmaceutical incompatibilities: Definition, classification, physical, chemical and therapeutic incompatibilities with examples.

Unit V

Semisolid dosage forms: Definitions, classification, mechanisms and factors influencing dermal penetration of drugs. Preparation of ointments, pastes, creams and gels. Excipients used in semi solid dosage forms. Evaluation of semi solid dosages forms