Course Title: 
Pharmacology III - Theory
Course Code: 
Year Taught: 
Undergraduate (UG)
School of Pharmacy

'Medicinal Chemistry III – Theory' is a course offered in the sixth semester of B. Pharm program at School of Pharmacy, Health Sciences campus, Amrita Vishwa Vidyapeetham.

Course Duration: 45 Hours


This subject is intended to impart the fundamental knowledge on various aspects (classification, mechanism of action, therapeutic effects, clinical uses, side effects and contraindications) of drugs acting on respiratory and gastrointestinal system, infectious diseases, immunopharmacology and in addition,emphasis on the principles of toxicology and chronopharmacology.


Upon completion of this course the student should be able to:

  1. Understand the mechanism of drug action and its relevance in the treatment of different infectious diseases
  2. Comprehend the principles of toxicology and treatment of various poisoning sand
  3. Appreciate correlation of pharmacology with related medical sciences.

Unit I (10 Hours)

1. Pharmacology of drugs acting on Respiratory system

  1. Anti -asthmatic drugs
  2. Drugs used in the management of COPD
  3. Expectorants and antitussives
  4. Nasal decongestants
  5. Respiratory stimulants

1. Pharmacology of drugs acting on the Gastrointestinal Tract

  1. Antiulcer agents.
  2. Drugs for constipation and diarrhoea.
  3. Appetite stimulants and suppressants.
  4. Digestants and carminatives.
  5. Emetics and anti-emetics.


Unit II (10 Hours)

3. Chemotherapy

  1. General principles of chemotherapy.
  2. Sale of Drugs – Wholesale, Retail sale and Restricted license. Offences and penalties
  3. Labeling & Packing of drugs- General labeling requirements and specimen labels for drugs and cosmetics,
  4. List of permitted colors. Offences and penalties.
  5. Administration of the Act and Rules – Drugs Technical Advisory Board, Central drugs
  6. Laboratory, Drugs Consultative Committee, Government drug analysts, Licensing authorities, controlling authorities, Drugs Inspectors

Unit III (10 Hours)

3. Chemotherapy

  1. Antitubercular agents
  2. Antileprotic agents
  3. Antifungal agents
  4. Antiviral drugs
  5. Anthelmintics
  6. Antimalarial drugs
  7. Antiamoebic agents

Unit IV (08 Hours)

5. Chemotherapy

  1. Urinary tract infections and sexually transmitted diseases.
  2. Chemotherapy of malignancy.

6. Immunopharmacology

  1. Immunostimulants
  2. Immunosuppressant

Protein drugs, monoclonal antibodies, target drugs to antigen, biosimilars

Unit V (07 Hours)

7. Principles of toxicology

  1. Definition and basic knowledge of acute, subacute and chronic toxicity.
  2. Definition and basic knowledge of genotoxicity, carcinogenicity, teratogenicity and mutagenicity
  3. General principles of treatment of poisoning
  4. Clinical symptoms and management of barbiturates, morphine, organophosphosphorus com- pound and lead, mercury and arsenic poisoning.

8. Chronopharmacology

  1. Definition of rhythm and cycles.
  2. Biological clock and their significance leading to chronotherapy.