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Course Detail

Course Name Structural Bioinformatics
Course Code BIF 409
Program M. Sc. in Bioinformatics
Semester Two
Credits Four
Year Taught 2019


Fundamentals of protein, DNA, RNA structure, macromolecular structure determination, X ray crystallography, NMR spectroscopy, Electron microscopy, Structure formats, molecular visualization, Protein structure evolution and SCOP database, CATH domain structure database, identifying structural domains in protein, prediction of protein – protein interaction from phylogenetic analysis, structure comparison and alignment, structural bioinformatics in drug discovery, CASP and CAFASP experiments, homology modeling, fold recognition methods, AB INITIO methods. Secondary structure prediction.

Text Books

  1. Structural bioinformatics, Philip E Bourne, HelgeWeisssig
  2. Protein Bioinformatics : An Algorithmic Approach to Sequence and Structure Analysis by Ingvar Eidhammer, et al;


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