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Dr. Subramania Iyer K.

Head of Department | Professor, Head & Neck Surgery, School of Medicine, Kochi

Qualification: MCh, MS
subu@aims.amrita.edu

Bio

With over four decades of unparalleled expertise, Dr. Subramania Iyer stands as a titan in the realm of surgical innovation and excellence. Having meticulously performed over 40,000+ major surgical procedures and more than 6,000+ free flap surgeries, his mastery in the field is undisputed. Dr. Iyer’s accolades include pioneering the first-hand transplants in the country and leading the centre with largest number of composite tissue allotransplants globally, a testament to his groundbreaking contributions. Dr. Iyer’s special interests lie in head and neck cancer surgery, secondary reconstruction, laryngeal reinnervation, and cutting-edge techniques like laser and robotic surgery, where he continues to push the boundaries of medical advancement. His contributions in field of medical training are pathbreaking with establishing the first three-year structured training programme in head and neck surgical oncology and Indias first and only masters training programme in deglutology and swallowing therapy.

Dr. Iyer is the author of over 50 scholarly papers and 3 book chapters relating to plastic surgery/ head and neck surgery. He has presented and published his work in national and international journals and forums. He also delivered 32 orations, 54 International lectures and over 250 National keynote lectures. Has published over 200 peer reviewed papers and book chapters

 

Publications

Journal Article

Year : 2021

Prosthetic Rehabilitation of surgically reconstructed mandible with increased crown height space

Cite this Research Publication : Journal of Prosthetic and Implant Dentistry: Vinodkrishnan, Manju V, Apurva T, Krishnapriya, Arjun Krishnadas, Pramod Subash, Subramania Iyer. Prosthetic Rehabilitation of surgically reconstructed mandible with increased crown height space. JPID – Volume 4 Issue 3 / May–August 2021

Year : 2021

Low PDL1 Expression in Tumour Infiltrating Lymphocytes Predicts Local Recurrence in Oral Squamous Cell Carcinoma.

Cite this Research Publication : Narayana Subramaniam, Ajit Nambiar, Sujan Dhar, Krishnakumar Thankappan, Dr. Manzoor K., Deepak Balasubramanian, Manjula Das, and Subramania Iyer, “Low PDL1 Expression in Tumour Infiltrating Lymphocytes Predicts Local Recurrence in Oral Squamous Cell Carcinoma.”, Indian Journal of Surgical Oncology, vol. 12, no. 2, pp. 408-414, 2021.

Publisher : Indian Journal of Surgical Oncology

Year : 2021

Combinatorial effect of nano whitlockite/nano bioglass with FGF-18 in an injectable hydrogel for craniofacial bone regeneration

Cite this Research Publication : Sivashanmugam Amirthalingam, Seunghun S. Lee, Mahalakshmi Pandian, Janarthanan Ramu, Dr. Subramania Iyer K., Nathaniel S. Hwang, and Dr. Jayakumar Rangasamy, “Combinatorial effect of nano whitlockite/nano bioglass with FGF-18 in an injectable hydrogel for craniofacial bone regeneration”, Biomaterials Science, vol. 9, pp. 2439-2453, 2021.

Publisher : Biomaterials Science, The Royal Society of Chemistry

Year : 2019

Evaluation of Osseointegration of Staged or Simultaneously Placed Dental Implants with Nanocomposite Fibrous Scaffolds in Rabbit Mandibular Defect

Cite this Research Publication : Manju V., Dr. Subramania Iyer K., Dr. Deepthy Menon, Shantikumar V Nair, and Dr. Manitha B. Nair, “Evaluation of Osseointegration of Staged or Simultaneously Placed Dental Implants with Nanocomposite Fibrous Scaffolds in Rabbit Mandibular Defect”, Materials Science and Engineering C, vol. 104, 2019.

Publisher : Materials Science and Engineering

Year : 2019

Wide Excision and Microvascular Reconstruction for Maxillomandibular Ameloblastomas: Local Control, Functional, and Esthetic Outcomes

Cite this Research Publication : Deepak Balasubramanian, Narayana Subramaniam, Sherry Peter, Manju V., Krishnakumar Thankappan, Dr. Subramania Iyer K., Arjun Krishnadas, “Wide Excision and Microvascular Reconstruction for Maxillomandibular Ameloblastomas: Local Control, Functional, and Esthetic Outcomes”, Journal of Head & Neck Physicians and Surgeons, vol. 6, p. 82, 2019.

Publisher : Journal of Head & Neck Physicians and Surgeons

Year : 2019

Robot-Assisted Surgery Avoids Mandibulotomy in a Case of Adenoid Cystic Carcinoma of Base of the Tongue.

Cite this Research Publication : S. Vidhyadharan, Krishnakumar Thankappan, Narayana Subramaniam, Ramu, J., Ajith, A., Deepak Balasubramanian, and Dr. Subramania Iyer K., “Robot-Assisted Surgery Avoids Mandibulotomy in a Case of Adenoid Cystic Carcinoma of Base of the Tongue.”, Craniomaxillofac Trauma Reconstr, vol. 12, no. 2, pp. 163-166, 2019.

Publisher : Craniomaxillofac Trauma Reconstr

Year : 2019

A Novel Surface Enhanced Raman Catheter for Rapid Detection, Classification, and Grading of Oral Cancer

Cite this Research Publication : Girish C. M., Dr. Subramania Iyer K., Dr. Krishnakumar T., GS, G., Dr. Manzoor K., and Shantikumar V Nair, “A Novel Surface Enhanced Raman Catheter for Rapid Detection, Classification, and Grading of Oral Cancer”, Advanced Healthcare Materials, vol. 8, no. 13:e1801557, 2019.

Publisher : Advanced Healthcare Materials

Year : 2019

Clinical Significance of Alloantibodies in Hand Transplantation – A Multicenter Study

Cite this Research Publication : E. Berglund, Ljungdahl, M. Andersen, Bogdanović, D., Berglund, D., Wadström, J., Kowalski, J., Brandacher, G., Kamińska, D., Kaufman, C. L., Talbot, S. G., Azari, K., Landin, L., Höhnke, C., Dwyer, K. M., Cavadas, P. C., Thione, A., Clarke, B., Kay, S., Wilks, D., Dr. Subramania Iyer K., Iglesias, M., Özkan, Ö., Özkan, Ö., Krapf, J., Weissenbacher, A., Petruzzo, P., and Schneeberger, S., “Clinical Significance of Alloantibodies in Hand Transplantation - A Multicenter Study”, Transplantation, 2019.

Publisher : Transplantation

Year : 2019

Organ Preservation Protocols in T4 Laryngeal Cancer: A Review of the Literature

Cite this Research Publication : Narayana Subramaniam, Deepak Balasubramanian, Reddy, R., Krishnakumar Thankappan, and Dr. Subramania Iyer K., “Organ Preservation Protocols in T4 Laryngeal Cancer: A Review of the Literature”, Indian J Surg Oncol, vol. 10, no. 1, pp. 149-155, 2019.

Publisher : Indian J Surg Oncol

Year : 2019

Validation of the Eighth Edition AJCC Staging System in Early T1 to T2 Oral Squamous Cell Carcinoma

Cite this Research Publication : S. Murthy, Low, T. - H. Hubert, Narayana Subramaniam, Deepak Balasubramanian, Sivakumaran, V., Anand, A., Vijayan, S. Nalumackal, Nambiar, A., Krishnakumar Thankappan, and Dr. Subramania Iyer K., “Validation of the Eighth Edition AJCC Staging System in Early T1 to T2 Oral Squamous Cell Carcinoma”, J Surg Oncol, vol. 119, no. 4, pp. 449-454, 2019.

Publisher : J Surg Oncol

Year : 2018

Outcomes Following Pharyngeal Reconstruction in Total Laryngectomy – Institutional Experience and Review of Literature

Cite this Research Publication : Deepak Balasubramanian, Narayana Subramaniam, Rathod, P., Murthy, S., Sharma, M., Jimmy Mathew, Krishnakumar Thankappan, and Dr. Subramania Iyer K., “Outcomes Following Pharyngeal Reconstruction in Total Laryngectomy - Institutional Experience and Review of Literature”, Indian J Plast Surg, vol. 51, no. 2, pp. 190-195, 2018.


Publisher : Indian J Plast Surg .

Year : 2018

Nanofibrous yarn reinforced HA-gelatin composite scaffolds promote bone formation in critical sized alveolar defects in rabbit model

Cite this Research Publication : Manju V., Anitha A., Dr. Deepthy Menon, Dr. Subramania Iyer K., Shantikumar V Nair, and Dr. Manitha B. Nair, “Nanofibrous yarn reinforced HA-gelatin composite scaffolds promote bone formation in critical sized alveolar defects in rabbit model”, Biomedical Materials, vol. 13, no. 6, p. 065011, 2018.

Publisher : Biomedical Materials

Year : 2018

Factors Affecting Survival in Surgically Salvaged Locoregional Recurrences of Squamous Cell Carcinoma of the Tongue

Cite this Research Publication : N. Subramaniam, Deepak Balasubramanian, Low, T. - H., Murthy, S., Clark, J. R., Thankappan, K., and Dr. Subramania Iyer K., “Factors Affecting Survival in Surgically Salvaged Locoregional Recurrences of Squamous Cell Carcinoma of the Tongue”, Journal of Oral and Maxillofacial Surgery, 2018.

Publisher : Journal of Oral and Maxillofacial Surgery,

Year : 2017

Soft emblaming of cadavers for training purposes:Optimising for long term use in tropical weather

Cite this Research Publication : R. Reddy, Subramania Iyer, Pillay, M., and Krishnakumar Thankappan, “Soft emblaming of cadavers for training purposes:Optimising for long term use in tropical weather”, Indian Journal of Plastic Surgery, 2017.

Publisher : Indian Journal of Plastic Surgery

Year : 2016

Early detection of oral cancers: Current status and future prospects

Cite this Research Publication : Dr. Subramania Iyer K., Thankappan, K., and Balasubramanian, D., “Early detection of oral cancers: Current status and future prospects”, Current Opinion in Otolaryngology and Head and Neck Surgery, vol. 24, pp. 110-114, 2016.

Publisher : Current Opinion in Otolaryngology and Head and Neck Surgery, Lippincott Williams and Wilkins

Year : 2014

Site-wise Differences in Adequacy of the Surgical resection Margins in Head and Neck Cancers

Cite this Research Publication : S. Vidhyadharan, Augustine, I., Kudpaje, A. S., Dr. Subramania Iyer K., and Dr. Krishnakumar T., “Site-wise Differences in Adequacy of the Surgical resection Margins in Head and Neck Cancers”, Indian journal of surgical oncology, vol. 5, no. 3, pp. 227–231, 2014.

Publisher : Indian journal of surgical oncology

Year : 2014

Defect components and reconstructive options in composite orbitomaxillary defects with orbital exenteration

Cite this Research Publication : Shawn T Joseph, Krishnakkumar Thankappan, Manju V., and Dr. Subramania Iyer K., “Defect components and reconstructive options in composite orbitomaxillary defects with orbital exenteration”, Journal of Oral and Maxillofacial Surgery, vol. 72, pp. 1869.e1-1869.e9, 2014.

Publisher : Journal of Oral and Maxillofacial Surgery

Year : 2013

Tracheoesophageal puncture site closure with single perforator-based deltopectoral flap

Cite this Research Publication : D. Balasubramanian, Dr. Subramania Iyer K., and Thankappan, K., “Tracheoesophageal puncture site closure with single perforator-based deltopectoral flap”, Head and Neck, vol. 35, pp. E60-E63, 2013.

Publisher : Head and Neck

Year : 2013

Propeller flaps in the closure of free fibula flap donor site skin defects

Cite this Research Publication : M. Sharma, Balasubramanian, D., Thankappan, K., Sampathirao, C. L., Mathew, J., Chavre, S., and Dr. Subramania Iyer K., “Propeller flaps in the closure of free fibula flap donor site skin defects”, Annals of Plastic Surgery, vol. 71, pp. 76-79, 2013.

Year : 2013

Cricotracheal reconstruction with free radial forearm flap and titanium mesh

Cite this Research Publication : D. Balasubramanian, Thankappan, K., Shetty, S., Jayaprasad, K., Mathew, J., and Dr. Subramania Iyer K., “Cricotracheal reconstruction with free radial forearm flap and titanium mesh”, Head and Neck, vol. 35, pp. E178-E180, 2013.

Publisher : Head and Neck

Year : 2012

Free tensor Fascia Lata-Iliac crest osteomusculocutaneous flap for reconstruction of combined maxillectomy and orbital floor defect

Cite this Research Publication : Dr. Subramania Iyer K., Chatni, S., and Kuriakose, M. A., “Free tensor Fascia Lata-Iliac crest osteomusculocutaneous flap for reconstruction of combined maxillectomy and orbital floor defect”, Annals of Plastic Surgery, vol. 68, pp. 52-57, 2012.

Publisher : Annals of Plastic Surgery

Year : 2011

Role of human papilloma virus in oral tongue squamous cell carcinoma

Cite this Research Publication : K. Ja Elango, Suresh, Aa, Erode, E. Mb, Subhadradevi, Lc, Ravindran, H. Kd, Iyer, S. Ke, Iyer, S. K. Rf, and Kuriakose, M. Aa, “Role of human papilloma virus in oral tongue squamous cell carcinoma”, Asian Pacific Journal of Cancer Prevention, vol. 12, pp. 889-896, 2011.

Publisher : Asian Pacific Journal of Cancer Prevention

Year : 2011

Mouth self-examination to improve oral cancer awareness and early detection in a high-risk population

Cite this Research Publication : K. Ja Elango, Anandkrishnan, Nb, Suresh, Aa, Iyer, S. Kb, Ramaiyer, S. Kc, and Kuriakose, M. Aad, “Mouth self-examination to improve oral cancer awareness and early detection in a high-risk population”, Oral Oncology, vol. 47, pp. 620-624, 2011.

Publisher : Oral Oncology

Year : 2011

Morbidity profile and functional outcome of modified facial translocation approaches for skull base tumors

Cite this Research Publication : V. Da Kekatpure, Rajan, G. Pb, Patel, Dc, Trivedi, N. Pa, Arun, Pc, Iyer, Sc, and Kuriakose, M. Aa, “Morbidity profile and functional outcome of modified facial translocation approaches for skull base tumors”, Skull Base, vol. 21, pp. 255-260, 2011.

Publisher : Skull Base

Year : 2011

Cross-chest liposuction in gynaecomastia

Cite this Research Publication : B. Murali, Vijayaraghavan, S., Kishore, P., Dr. Subramania Iyer K., Jimmy, M., Sharma, M., Paul, G., and Chavare, S., “Cross-chest liposuction in gynaecomastia”, Indian Journal of Plastic Surgery, vol. 44, pp. 81-86, 2011. doi: 10.4103/0970-0358.81451

Publisher : Indian Journal of Plastic Surgery

Year : 2010

Tensor Facia Lata-iliac crest osteocutaneous flap for orbitomaxillary reconstruction: A preliminary report

Cite this Research Publication : Dr. Subramania Iyer K. and Kuriakose, M., “Tensor Facia Lata-iliac crest osteocutaneous flap for orbitomaxillary reconstruction: A preliminary report”, Indian Journal of Plastic Surgery, vol. 43, pp. 8-13, 2010.

Publisher : Indian Journal of Plastic Surgery

Year : 2009

Free radial forearm adiposo-fascial flap for inferior maxillectomy defect reconstruction

Cite this Research Publication : Ka Thankappan, Trivedi, N. Pa, Sharma, Ma, Kuriakose, M. Aa, and Iyer, Sab, “Free radial forearm adiposo-fascial flap for inferior maxillectomy defect reconstruction”, Indian Journal of Plastic Surgery, vol. 42, pp. 100-103, 2009.

Publisher : Indian Journal of Plastic Surgery

Year : 2009

Esthetic and Anatomic Basis of Modified Lateral Rhinotomy Approach

Cite this Research Publication : Ka Thankappan, Sharan, Rb, Iyer, Sc, and Kuriakose, M. Ad, “Esthetic and Anatomic Basis of Modified Lateral Rhinotomy Approach”, Journal of Oral and Maxillofacial Surgery, vol. 67, pp. 231-234, 2009.

Publisher : Journal of Oral and Maxillofacial Surgery

Year : 2008

Comparison of quality of life in advanced laryngeal cancer patients after concurrent chemoradiotherapy vs total laryngectomy

Cite this Research Publication : N. P. Trivedi, Swaminathan, D. K., Thankappan, K., Chatni, S., Kuriakose, M. A., and Dr. Subramania Iyer K., “Comparison of quality of life in advanced laryngeal cancer patients after concurrent chemoradiotherapy vs total laryngectomy”, Otolaryngology - Head and Neck Surgery, vol. 139, pp. 702-707, 2008.

Publisher : Otolaryngology - Head and Neck Surgery

Conference Paper

Year : 2023

Rapid Detection of Penetration-Aspiration from Fluoroscopic Videos in Dysphagia Patients

Cite this Research Publication : Sanjeevi, G., Gopalakrishnan, U., Pathinarupothi, R.K., Arya, C.J. and Iyer, S., 2023, December. Rapid Detection of Penetration-Aspiration from Fluoroscopic Videos inDysphagia Patients. In 2023 IEEE 23rd International Conference on Bioinformatics and Bioengineering (BIBE) (pp. 409-413). IEEE Computer Society.

Publisher : IEEE

Book

Year : 2018

Dysphagia Management in Head and Neck Cancers A Manual and Atlas: A Manual and Atlas

Cite this Research Publication : Krishnakumar Thankappan, Dr. Subramania Iyer K., and Menon, J. R., Dysphagia Management in Head and Neck Cancers A Manual and Atlas: A Manual and Atlas. 2018.

Publisher : (2018)

Qualification
  • MS (Otorhinolaryngology)
  • MCh (Plastic Surgery)
  • FRCS
  • Specialised Fellowship Training in Conservative Laryngeal Surgery, Robotic Surgery, Craniofacial Surgery and Robotic Surgery
  • Fellowship in Craniofacial Surgery – Hospital G. Gonsalves , Mexico City 1996 (with Prof. Ortiz Monasterio).
  • UICC Fellowship in Laryngeal Surgery- Center Oscar Lambert, Lille, France 2002 (with Prof J.L.Lefebvre).
  • UICC Fellowship in Tissue Engineering – Rice University Houston Texas 2008 (with Prof Antonios Mikos).
Recognitions
  • External Examiner – Singapore Board of Plastic surgeons.
  • Special Honors and Awards
  • Kamani Gold Medal for the best outgoing post graduate, AIIMS, New Delhi.
  • Peet Prize for best Innovative work in Plastic Surgery in India awarded by association of Plastic Surgeons of India 2007.
  • Peet Prize for best Innovative work in Plastic Surgery in India awarded by association of Plastic Surgeons of India 2008.
  • Best Paper published award Association of plastic surgeons of India 2012.
  • Distinguished Overseas Lecture award Royal Australian college of Surgeons Annual meeting Perth 6-8 May 2010.
  • Presidium member Eurasian Summit of Cancer leaders Moscow March 23-24 , 2010.
  • Member – world cancer leaders summit , UICC World cancer congress Shengzen , China Aug 18-20, 2010.
  • Oration Andhra Pradesh Association Of ENT surgeons annual meeting 2008.
  • Oration Karnataka Association of ENT surgeons 2012.
  • Oration Tamil Nadu association of ENT surgeons 2012.
  • Oration Delhi Association of ENT surgeons 2013.
  • Oration Kerala Association of Maxillofacial surgeons 2013.
  • Oration Karnataka Association of Maxillofacial surgeons 2011.
  • FHNO Oration Asia Pacific meeting of head and neck oncology 2011.
  • Paches oration Eurasian Head and Neck Oncology Meeting Kazakhstan 2010.
  • Team leader BMJ surgical team- Southeast Asia of the year 2015
  • APSI best research project award 2013 ,2014,2016,2017
  • Rotary ‘for the sake of service’ award Kochi 2016
  • National Organ and Tissue transplant organisation (NOTTO) award for promotion of transplant activities 2018 and 2021
  • GAPIO-Siemens Award for excellence in medical care 2018
  • Honorary Membership Taiwanese Head and Neck society 2019
  • Excellence in service to Humanity award in connection with Azadi Ka amrit Mahotsav -Income Tax Kerala Circle 2022
  • Lifetime Achievement award Association of Maxillofacial surgeons of India 2022
  • Lifetime achievement award Foundation for head and enck Oncology of India 2023
  • Visiting Professor Pantei National Cancer centre and RIPAS hospital Brunei 2010 till date
  • International Faculty Member AOCMF 2012 onwards
Memberships
  • Foundation for Head & Neck Oncology of India.
  • Indian Society of Facial Plastic and Reconstructive Surgery.
  • Association of Plastic Surgeons of India.
  • Association of Otolaryngologists of India.
  • Indian Cleft and Craniofacial Society.
  • Indian Society of Oncology.
  • International Academy of Oral Oncology.
  • Indian Society of Reconstructive Microsurgery.
Roles
  • Chairman, Educational Subcommittee Kerala Association of Plastic Surgeons, 2004-2007.
  • Treasurer, Foundation for Head & Neck Oncology of India, 2001-2003.
  • President, Indian Society of Facial Plastic and Reconstructive Surgery, 2002-2004.
  • Secretary, Foundation for Head & Neck Oncology of India, 2003-2005.
  • Member, Governing Body, Foundation for Head & Neck Oncology of India, 2005-till date.
  • President, Head and Neck Cooperative Group (multicentre national research group) 2010 till date.
  • President, Foundation for Head & Neck Oncology of India, 2007-2009.
  • Secretary, Indian Society of Reconstructive Microsurgery, 2008 –till date.
  • President, Eurasian Society of head and Neck Oncology, 2010-2012.
  • Member, Governing Body, Eurasian Federation Of Oncology (EAFO), 2012-2016.
  • Member Executive Committee of Association of Plastic Surgeons of India 2011-2014.
  • President Kerala Association of Plastic Surgeons 2014-2015.
  • Association of Plastic surgeons of India Foundation for Head and Neck Oncology
  • Indian Society of Reconstructive Microsurgery
  • International Society for Vascularised Composite allotransplants
  • Eurasian Society of Head and neck Oncology
  • Head and Neck Cooperative research group of India
  • Asia Pacific Thyroid surgeons’ society
  • Foundation for dysphagia research and education of India
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