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7 – Chitosan–Nanohydroxyapatite Nanocomposite for Bone-Tissue Regeneration

Publication Type : Journal Article

Thematic Areas : Medical Sciences

Publisher : Nanocomposites for Musculoskeletal Tissue Regeneration, Woodhead Publishing, Oxford .

Source : Nanocomposites for Musculoskeletal Tissue Regeneration, Woodhead Publishing, Oxford, p.161 - 174 (2016)

Url :

ISBN : 9781782424529

Keywords : Ceramics, Hybrid composites, Nanocomposites, Polymers, Polymer–matrix composites (PMCs)

Campus : Kochi

School : School of Medicine

Year : 2016

Abstract : In the past two decades, significant research has been conducted to make artificial bone with the use of metals, ceramics, and polymers. Composite of biopolymer (chitosan) and bioceramic (nanohydroxyapatite—nHA) is a promising approach and these are widely studied biomaterials for bone-graft substitution. In the present review, we discussed the preparative method, mechanical properties, cell proliferation, alkaline phosphatase activity, mineralization effect and innbsp;vivo study of chitosan–nHA composite for bone-tissue regeneration. Chitosan–nHA composites containing third-component systems (synthetic polymers, growth factors, and stem cells) were discussed for better bone formation. Hence, the composite of chitosan–nHA will be a promising biomaterial for bone-tissue engineering .

Cite this Research Publication : J. Venkatesan, Jayakumar, R., Anil, S., and Kim, S. - K., “7 - Chitosan–Nanohydroxyapatite Nanocomposite for Bone-Tissue Regeneration”, Nanocomposites for Musculoskeletal Tissue Regeneration, pp. 161 - 174, 2016.

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