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A study on clinical pharmacist interventions in the management of sepsis in a tertiary care hospital

Publication Type : Journal Article

Publisher : International Journal of Pharmaceutical Sciences Review and Research

Source : International Journal of Pharmaceutical Sciences Review and Research, Volume 40, Issue 2, p.109-114 (2016)

Campus : Kochi

School : School of Pharmacy

Center : Amrita Institute of Medical Science

Department : Pharmaceutics

Verified : Yes

Year : 2016

Abstract : Sepsis is a disorder categorized by systemic response to infection that can swiftly lead to death. Drug Related Problems (DRPs) have been shown to be happening in hospitalized patients. In sepsis patients this may worsen prognosis. We aimed to analyse impact of clinical pharmacist’s interventions on sepsis patients with objectives of identifying and resolving drug related problems (DRPs) if any. An interventional study was conducted and retrospective data of previous one year was taken as control group. Patients clinically diagnosed as sepsis with age ≥ 18 years and admitted in selected ICUs, were included but Patients who got discharged against medical advice were excluded. The selected medical record numbers by convenient sampling were randomized using graph pad software to get 100 samples in control group. Prospective cases that met study criteria and admitted every third day were recruited. In addition to documented evidence about each patient, direct interaction with patients and Health care providers (HCPs) were carried out during prospective data collection. An aggregate of 57 and 92 DRPs were identified from retrospective (100) and prospective populace (100) respectively. About 77.04% of problems could be totally resolved in consultation with HCPs. High acceptance rate of our interventions highlights the importance of clinical pharmacists working in tandem with other health care providers in critical care areas for better patient outcome. So a fulltime clinical pharmacist in intensive care units can provide a consistent level of pharmaceutical care with minimum drug related problems in life threatening conditions like sepsis.

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