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Action potential and bursting phenomena using analog electrical neuron

Publication Type : Conference Paper

Publisher : A2CWiC'10

Source : Proceedings of the 1st Amrita ACM-W Celebration of Women in Computing in India, A2CWiC'10, Coimbatore (2010)

Url :

ISBN : 9781450301947

Keywords : Action Potentials, Active current, Analog circuits, Arithmetic operations, Biophysical model, Biophysics, Capacitance change, Circuit models, Differential equations, electrical analog neuron, Integrator circuits, Ion channel, Ionic channels, Ions, Membrane potentials, Membrane resistance, Nerve cells, Neuromorphic engineering, Neuromorphic networks, Neuron model, neuronal biophysics, Neuronal model, Neurons, Passive components, Passive properties, Potassium currents, Teaching practices, Virtual lab, Voltage model

Campus : Amritapuri

School : School of Biotechnology

Center : Biotechnology

Department : biotechnology

Verified : Yes

Year : 2010

Abstract : A neuron or nerve cell has passive components due to resistive-capacitive nature of circuitry and active current components contributed by ion channels. Biophysical neurons represent active and passive components by differential equations. The differential equations of the biophysical model were integrated by making arithmetic operations on voltage model circuits. Analog neuronal model using voltage integrator circuits is the main focus of this paper. The work involves two circuit models and also addresses design and passive properties of analog neuron model along with the effects of Na+ and K+ ionic channels. In the first simpler circuit, an action potential was generated. In the enhanced second model, sodium and potassium currents were generated separately along with action potential. Impacts of noise and various geometrical signals on the action potential and ionic channels were studied to analyze the effects of membrane resistance and capacitance changes in membrane potential and ionic channels. Besides its use in neuromorphic network research, the model has been successfully in virtual labs and for teaching practice. © 2010 ACM.

Cite this Research Publication : M. Parangan, Aravind, C., Parasuraman, H., Dr. Krishnashree Achuthan, Nair, B., and Dr. Shyam Diwakar, “Action potential and bursting phenomena using analog electrical neuron”, in Proceedings of the 1st Amrita ACM-W Celebration of Women in Computing in India, A2CWiC'10, Coimbatore, 2010

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