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An Improved Upper Bound for Genome Rearrangement by Prefix Transpositions

Publication Type : Conference Paper

Publisher : Advanced Computing and Communication Technologies for High Performance Applications (ACCTHPA), IEEE

Source : 2020 Advanced Computing and Communication Technologies for High Performance Applications (ACCTHPA), IEEE (2020)

Url : https://ieeexplore.ieee.org/document/9213217

Keywords : DNA sequencing, genomes, Permutations, Sorting, transpositions

Campus : Amritapuri

School : School of Arts and Sciences

Department : Mathematics

Year : 2020

Abstract : Genome rearrangement problems in Genomics are studied extensively due to their significance in the evolution theory and detection of hereditary illnesses. This is a challenging problem in Big Data science for Computational Biologist due to the large number of DNA sequences being generated, explored, and analyzed. Identifying the position of genes in a genome as a permutation has transformed this problem into a sorting of permutations with certain constraints. Sorting permutations by different types of reversals and transpositions have been an active area of research due to their high resemblance to genome rearrangements. A prefix transposition is a particular type of transposition where the first few symbols of the permutation are moved to another fixed position. In this paper, we provide a better upper bound for sorting permutations by prefix transpositions.

Cite this Research Publication : Pramod P. Nair and Sundaravaradhan, R., “An Improved Upper Bound for Genome Rearrangement by Prefix Transpositions”, in 2020 Advanced Computing and Communication Technologies for High Performance Applications (ACCTHPA), 2020.

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