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Aticancer activity of chloroform extract of Helicteres ISORA

Publication Type : Journal Article

Publisher : International Journal of Pharmacy and Technology

Source : International Journal of Pharmacy and Technology, vol. 3, pp. 2560-2564, 2011

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Keywords : alkaloid, antineoplastic activity, antineoplastic agent, article, breast cancer, cancer inhibition, carbohydrate, cell strain MCF 7, cell viability, concentration response, controlled study, drug cytotoxicity, drug potency, drug screening, flavonoid, Helicteres isora, Helicteres isora extract, human, human cell, phytochemistry, plant extract, Sterculiaceae, tannin derivative, unclassified drug

Campus : Kochi

School : School of Pharmacy

Department : Pharmaceutical Chemistry & Analysis

Year : 2011

Abstract : Helicteres isora belongs to the family sterculiaceae is an ayurvedic is distributed widely in forest throughout india and are commonly known as east india screw tree spi_sup1spii_sup. Is a medicinally important sub-deciduous shrub or small tree.almost all parts of the plant are used in traditional medicinal system for curing various diseases. its fruit,Root and bark possess significant antidiabetic. Antioxidant,Antimicrobial and hypolipidemic activity. the fruit of helicterusisora after collection,Authentication and drying was extracted with chloroform using soxhlet extractor.the present study was aimed to determine the preliminary phytochemical evaluation and cytotoxicity study of the chloroform extract of helicteres isora on MCF - 7 cell line (human breast cancer) by MTT assay method. the preliminary phytochemical evaluation showed the presence of carbohydrates,Flavonoids,Tannins and alkaloidsspi_sup2spii_sup.its cytotoxic evaluation showed a potent action against to MCF - 7 (michigan cancer foundation - 7) cell line.

Cite this Research Publication : E. Varghese, Dr. S. Sathianarayanan, Gopal, R. V., Nair, A., Chittethu, A. B., and Anson, T. A., “Aticancer activity of chloroform extract of Helicteres ISORA”, International Journal of Pharmacy and Technology, vol. 3, pp. 2560-2564, 2011

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