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Carbamazepine-induced toxic epidermal necrolysis: A case report

Publisher : Asian Journal of Pharmaceutical and Clinical Research

Year : 2018

Abstract : Toxic epidermal necrolysis (TEN) is a life-threatening dermatological disorder characterized by erythematous lesions, necrosis, exfoliation, sepsis, and death. This may be due to different reasons such as chemical exposure, systemic infections, or some reactions of drugs such as carbamazepine, phenytoin, allopurinol, lamotrigine, and nonsteroidal anti-inflammatory drugs. In this case, the patient was on carbamazepine for the management of alcohol withdrawal symptoms. Moreover, this might be the reason for the occurrence of TEN. For his condition, he had given corticosteroids, antibiotics for sepsis, and other supportive measures.

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