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Chrysomycin A inhibits the topoisomerase I of Mycobacterium tuberculosis

Publication Type : Journal Article

Publisher : Journal of antibiotics

Source : Journal of antibiotics 75, 226–235 (2022

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Campus : Kochi

School : School of Biotechnology

Department : biotechnology

Year : 2021

Abstract : Bioplastics are startlingly growing in a rapid rate in the field of packaging to introduce newer high-end green materials. Nanocellulose is biodegradable, bio-based and can be effectively utilized for developing novel bioplastics using plasticizers and fillers. Triethylcitrate is used in the present study because of its non-toxic nature and better flowability of the suspension for solvent casting. The incorporation of some active filler can contribute to better bioplastics with improved properties. Frankincense is a natural substance extracted from Boswellia serrata tree that possesses numerous beneficial properties to be applicable as packaging materials. The biocomposite thin films were characterized using FTIR, XRD, FESEM and investigated the physical properties, soil burial degradability, antibacterial and antifungal properties. This study revealed the possibility of developing new biodegradable plastics with high shelf life for food packaging applications due to their predominant antibacterial and antifungal properties.

Cite this Research Publication : Muralikrishnan, B., Edison, L. K., Dusthackeer, A., Reji, J. G., Ramachandran, R., Aravind Madhavan., & Kumar, R. A. (2021). Chrysomycin A inhibits the topoisomerase I of Mycobacterium tuberculosis. Journal of antibiotics 75, 226–235 (2022). (IF 3.424).

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