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Publication Type : Journal Article
Thematic Areas : Medical Sciences, Nanosciences and Molecular Medicine
Publisher : Clinical Microbiology and Infection,
Source : Clinical Microbiology and Infection, Volume 27, p.1118-1119. (2021)
Campus : Kochi
School : Center for Nanosciences, School of Medicine
Center : Amrita Center for Nanosciences and Molecular Medicine Move, Nanosciences
Department : Nanosciences and Molecular Medicine, Microbiology
Year : 2021
Abstract : A boy in his teens on long-term treatment with mycophenolate mofetil and steroids presented with a nodular swelling on the volar aspect of the right forearm. During the previous 2 months, he had experienced creeping eruptions of the right arm. The patient had never travelled outside India. Physical examination found a tender, well-defined 1 × 1-cm, mobile swelling in the subcutaneous plane with fixing of the skin. Ultrasound scan of the swelling revealed a 1.3 × 0.9 cm hyperechoic lesion suggestive of a live worm (Fig. 1, and see Supplementary material, video S1). Laboratory investigations showed a normal blood leucocyte count without eosinophilia. The excised cystic lesion on sectioning revealed a white thread-like, live worm in a coiled state (see Supplementary material, videos S2, S3). Scanning electron microscopy of the worm surface showed longitudinal ridges and transverse striations (Fig. 2A,B) ruling out Dirofilaria immitis. The worm was subjected to multiplex PCR, which identified it as Dirofilaria repens; however, sequencing of the cyclo-oxygenase type 1 gene identified it as Candidatus Dirofilaria hongkongensis.
Cite this Research Publication : Dr. Anil Kumar V., Aswin Prabhakaran, Sanju Sherji, Dr. Lalitha Biswas, Arya Ramachandran, Mohan Abraham, and Dr. Raja Biswas, “Dirofilarial adult worms can also dance.”, Clinical Microbiology and Infection, vol. 27, pp. 1118-1119., 2021.