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Effect of ZnO nanoparticles on nasopharyngeal cancer cells viability and respiration

Publication Type : Journal Article

Thematic Areas : Nanosciences and Molecular Medicine

Publisher : Applied Physics Letters

Source : Applied Physics Letters, Volume 102, Number 11 (2013)

Url : is external)

Keywords : Cell respiration, cell viability, Cells, Chemical process, Dose-dependent, Metal Nanoparticles, Nasopharyngeal cancer, scanning electrochemical microscopy, scanning electron microscopy, Scanning probe microscopy, Therapeutic drugs, ZnO nanoparticles

Campus : Kochi

School : Center for Nanosciences

Center : Amrita Center for Nanosciences and Molecular Medicine Move, Nanosciences

Department : Nanosciences

Verified : Yes

Year : 2013

Abstract : Development of a therapeutic drugs based on nanoparticles requires a better understanding of the mechanism of selective cyto-toxic effects of nanopaticles over cancer cells. Scanning electrochemical microscopy provides opportunity to measure the real time chemical process at cell proximity in the presence of nanoparticle. Herein, the respiration process in nasopharyngeal cancer cells is investigated with the help of scanning electrochemical microscopy. The cell viability has been tested with MTT assay. The results show that ZnO nanoparticles have time and dose dependent effect in nasopharyngeal cancer cells and the cell respiration rate decreases with time. © 2013 American Institute of Physics.

Cite this Research Publication : Ra Prasanth and Gopinath, Db, “Effect of ZnO nanoparticles on nasopharyngeal cancer cells viability and respiration”, Applied Physics Letters, vol. 102, 2013.

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