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Efficient syntheses of ($pm$)[2-2H2] mevalonolactone and ($pm$)[2-2H2] homomevalonolactone

Publication Type : Journal Article

Thematic Areas : Biotech

Publisher : Wiley Online Library

Source : Journal of Labelled Compounds and Radiopharmaceuticals, Wiley Online Library, Volume 25, Number 1, p.111–115 (1988)

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Keywords : (±) [2-2H2]homomevalonolactone, (±) [2-2H2]mevalonolactone, juvenile hormone, NMR spectroscopy, Trimethylsilyl [2-2H3]acetate

Campus : Amritapuri

School : School of Biotechnology

Center : Biotechnology, Phytochemistry Labs, Sanitation Biotechnology

Department : biotechnology, Chemistry

Year : 1988

Abstract : Efficient syntheses of (±) [2-2H2]mevalonolactone and (±) [2-2H2]homomevalonolactone involving condensations of lithiotrimethylsilyl [2-2 H2]acetate with appropriate 3-oxo-alcohols are described. Regiospecificity of the label was established by NMR spectroscopy.

Cite this Research Publication : A. Banerji and Kalena, G. P., “Efficient syntheses of ($\pm$)[2-2H2] mevalonolactone and ($\pm$)[2-2H2] homomevalonolactone”, Journal of Labelled Compounds and Radiopharmaceuticals, vol. 25, pp. 111–115, 1988.

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