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Engineering interventions in industrial filamentous fungal cell factories for biomass valorization

Publication Type : Journal Article

Publisher : Bioresorce Technology

Source : Bioresorce Technology, 2022. 126209

Url :

Campus : Kochi

School : School of Biotechnology

Department : biotechnology

Year : 2022

Abstract : Filamentous fungi possess versatile capabilities for synthesizing a variety of valuable bio compounds, including enzymes, organic acids and small molecule secondary metabolites. The advancements of genetic and metabolic engineering techniques and the availability of sequenced genomes discovered their potential as expression hosts for recombinant protein production. Remarkably, plant-biomass degrading filamentous fungi show the unique capability to decompose lignocellulose, an extremely recalcitrant biopolymer. The basic biochemical approaches have motivated several industrial processes for lignocellulose biomass valorisation into fermentable sugars and other biochemical for biofuels, biomolecules, and biomaterials. The review gives insight into current trends in engineering filamentous fungi for enzymes, fuels, and chemicals from lignocellulose biomass. This review describes the variety of enzymes and compounds that filamentous fungi produce, engineering of filamentous fungi for biomass valorisation with a special focus on lignocellulolytic enzymes and other bulk chemicals.

Cite this Research Publication : Aravind Madhavan, KB Arun, Raveendran Sindhu, Anju Alphonsa Jose, Arivalagan Pugazhendhi, Parameswaran Binod, Ranjna Sirohi, Reshmy R, Mukesh Kumar Awasthi. Engineering interventions in industrial filamentous fungal cell factories for biomass valorization. Bioresorce Technology, 2022. 126209. (IF-11.889). (First and corresponding author).

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