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Fabrication and testing of handheld electronic meter for colorimetric paper microfluidic devices

Publication Type : Journal Article

Thematic Areas : Biotech

Publisher : Materials Today: Proceedings

Source : Materials Today: Proceedings, Volume 33, p.2421-2425 (2020)

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Keywords : Arduino uno, Paper-based sensor, Point-of-care-testing, Primary color shade, RGB color sensor, Total protein detection

Campus : Amritapuri, Coimbatore

School : School of Physical Sciences, School of Biotechnology, School of Engineering

Center : Biosensor Research Lab, Biotechnology

Department : Department of Sciences, biotechnology, Sciences

Year : 2020

Abstract : This paper reports the development and fabrication of a low-cost handheld point of care device that can quantify the concentration of biomarkers using a paper microfluidic assay. The commercially available light-to-digital converting sensor was used to achieve this objective. This RGB sensor was efficient in the digital values of the red, green, and blue components of the sample or object. It has an inbuilt white LED source, an array of photodiodes with color filters, an analog-to-digital converter module, and also an IR blocking filter. The sensor was interfaced with the Arduino UNO board, and the corresponding results were displayed on the serial monitor. This device was tested for manually prepared primary color samples and also for total protein. The colorimetric detection of protein was performed for 1 g dL-1 to 14 g dL-1 concentrations on a paper microfluidic device. The change in color intensity of the paper device with an increase in total protein concentration was monitored and calibrated the device for real sample analysis.

Cite this Research Publication : M. S. Iyer, Resmi, P. E., Shyamlal, C. P., Suneesh, P. Vasu, and Dr. Satheesh Babu T. G., “Fabrication and testing of handheld electronic meter for colorimetric paper microfluidic devices”, Materials Today: Proceedings, vol. 33, pp. 2421-2425, 2020.

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