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Facilitating Neuroscience Surveys using a Meta Path based Neuroinformatics Text-Mining Platform

Publication Type : Conference Paper

Thematic Areas : Learning-Technologies, Medical Sciences, Biotech

Publisher : Proceedings of the International symposium on Translational Neuroscience & XXXII Annual Conference of the Indian Academy of Neurosciences, NIMHANS, Bangalore , India

Source : Proceedings of the International symposium on Translational Neuroscience & XXXII Annual Conference of the Indian Academy of Neurosciences, NIMHANS, Bangalore , India (2014)

Campus : Amritapuri

School : School of Biotechnology

Center : Amrita Mind Brain Center, Biotechnology, Computational Neuroscience and Neurophysiology

Department : biotechnology

Year : 2014

Abstract : We have developed a program NeuroText to populate the neuroscience databases in SenseLab (http://senselab.med.yale.edu/senselab) by mining the natural language text of neuroscience articles. NeuroText uses a two-step approach to identify relevant articles. The first step (pre-processing), aimed at 100% sensitivity, identifies abstracts containing database keywords. In the second step, potentially relveant abstracts identified in the first step are processed for specificity dictated by database architecture, and neuroscience, lexical and semantic contexts. NeuroText results were presented to the experts for validation using a dynamically generated interface that also allows expert-validated articles to be automatically deposited into the databases. Of the test set of 912 articles, 735 were rejected at the pre-processing step. For the remaining articles, the accuracy of predicting database-relevant articles was 85%. Twenty-two articles were erroneously identified. NeuroText deferred decisions on 29 articles to the expert. A comparison of NeuroText results versus the experts’ analyses revealed that the program failed to correctly identify articles’ relevance due to concepts that did not yet exist in the knowledgebase or due to vaguely presented information in the abstracts. NeuroText uses two “evolution” techniques (supervised and unsupervised) that play an important role in the continual improvement of the retrieval results. Software that uses the NeuroText approach can facilitate the creation of curated, special-interest, bibliography databases.

Cite this Research Publication : Nidheesh Melethadathil, Dr. Bipin G. Nair, and Dr. Shyam Diwakar, “Facilitating Neuroscience Surveys using a Meta Path based Neuroinformatics Text-Mining Platform”, in Proceedings of the International symposium on Translational Neuroscience & XXXII Annual Conference of the Indian Academy of Neurosciences, NIMHANS, Bangalore , India, Nov 1-Nov 3,2014.

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