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Highly Sensitive and Wide-range Nonenzymatic Disposable Glucose Sensor based on a Screen printed carbon electrode modified with reduced graphene oxide and Pd-CuO Nanoparticles

Publication Type : Journal Article, Book Chapter

Thematic Areas : Biotech

Publisher : Microchimica Acta

Source : Microchimica Acta, Springer-Verlag Wien (2015)

Url :

Campus : Amritapuri, Coimbatore

School : School of Biotechnology, School of Engineering

Center : Biosensor Research Lab, Biotechnology

Department : biotechnology, Sciences

Year : 2015

Abstract : A nanocomposite consisting of reduced graphene oxide decorated with palladium-copper oxide nanoparticles (Pd-CuO/rGO) was synthesized by single-step chemical reduction. The morphology and crystal structure of the nanocomposite were characterized by field-emission scanning electron microscopy, high resolution transmission electron microscopy and X-ray diffraction analysis. A 3-electrode system was fabricated by screen printing technology and the Pd-CuO/rGO nanocomposite was dropcast on the carbon working electrode. The catalytic activity towards glucose in 0.2 M NaOH solutions was analyzed by linear sweep voltammetry and amperometry. The steady state current obtained at a constant potential of +0.6 V (vs. Ag/AgCl) showed the modified electrode to possess a wide analytical range (6 μM to 22 mM), a rather low limit of detection (30 nM), excellent sensitivity (3355 μA∙mM−1∙cm−2) and good selectivity over commonly interfering species and other sugars including fructose, sucrose and lactose. The sensor was successfully employed to the determination of glucose in blood serum. [Figure not available: see fulltext.] © 2015 Springer-Verlag Wien

Cite this Research Publication : K. Dhara, Dr. Ramachandran T., Dr. Bipin G. Nair, and Dr. Satheesh Babu T. G., “Highly sensitive and wide-range nonenzymatic disposable glucose sensor based on a screen printed carbon electrode modified with reduced graphene oxide and Pd-CuO nanoparticles”, Microchimica Acta, 2015

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