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Insect antifeedant activity of furochromones: Structure-activity relationships

Publication Type : Journal Article

Thematic Areas : Biotech

Publisher : ACS Publications,

Source : Journal of natural products, ACS Publications, Volume 56, Number 5, p.671–675 (1993)

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Campus : Amritapuri

School : School of Biotechnology

Center : Biotechnology, Phytochemistry Labs

Department : biotechnology, Chemistry

Year : 1993

Abstract : Thirty chromone derivatives, both synthetic and natural, were assayed for feeding deterrent activity against Spodoptera litura larvae to establish structure-activity relationships. Among the compounds tested, furochromones with alkoxy substituents at C-4 or C-9 exhibited maximum feeding deterrent activity. Loss of activity was noticed with the degradation or saturation of either of the heterocyclic rings. Substitution of C-7 methyl of the gamma-pyrone ring and dealkylation of C-4 or C-9 methoxyl also caused considerable reduction in feeding deterrent activity.

Cite this Research Publication : D. Lakshmicha Luthria, Ramakrishnan, V., and Banerji, A., “Insect antifeedant activity of furochromones: Structure-activity relationships”, Journal of natural products, vol. 56, pp. 671–675, 1993.

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